中央研究院 生物化學研究所

研究領域與專長

Research Background:

Molecular Cell Biology, Biochemistry, Genetics, System Biology.

Manager of Bio-Imaging Core Facility (BICF) Supporting users as follows:

• Advanced imaging systems
  Fluorescence microscope; Laser-scanning confocal microscopes; High-content screening station; Flow cytometers; Bioluminescence and Chemiluminescence Imager.
• Efficient technical consultation
  Design of imaging experiments, choice of training on suitable imaging systems. and subsequent image processing, visualization and analysis.
• Training courses and technician-assisted operation of instruments.

學經歷

• 2012-2018   博士，國立台灣大學生命科學學院基因體暨系統生物學位學程
• 2011-2012   碩士，國立暨南國際大學應用化學所
• 2008-2011   學士，國立暨南國際大學應用化學系

• 2022 – 迄今   研究助技師，生物影像核心設施，中央研究院生物化學研究所
• 2021 – 2022   博士後，中央研究院生物化學研究所
• 2019 – 2021   博士後（研發替代役），中央研究院生物化學研究所

主要著作

WAKE-mediated modulation of cVA perception via a hierarchical neuro-endocrine axis in Drosophila male-male courtship behaviour. 
Chen SL, Liu BT, Lee WP, Liao SB, Deng YB, Wu CL, Ho SM, Shen BX, Khoo GH, Shiu WC, Chang CH, Shih HW, Wen JK, Lan TH, Lin CC, Tsai YC, Tzeng HF & Fu TF 
Nat Commun. (2022)

Drosophila as a model to study autophagy in neurodegenerative diseases and digestive tract. 
Tzou FY, Wen JK, Yeh JY, Huang SY, Chen GC, Chan CC 
IUBMB Life. (2022)

PTPN9-mediated dephosphorylation of VTI1B promotes ATG16L1 precursor fusion and autophagosome formation. 
Chou HY, Lee YT, Lin YH, Wen JK, a , Peng WH, Hsieh PL, Lin SY, Hung CC, and Chen GC 
Autophagy. (2021)

Atg9 antagonizes TOR signaling to regulate intestinal cell growth and epithelial homeostasis in Drosophila. 
Wen JK, Wang YT, Chan CC, Hsieh CW, Liao HM, Hung CC, Chen GC 
Elife. (2017)

PPL2ab neurons restore sexual responses in aged Drosophila males through dopamine. 
Kuo SY, Wu CL, Hsieh MY, Lin CT, Wen RK, Chen LC, Chen YH, Yu YW, Wang HD, Su YJ, Lin CJ, Yang CY, Guan HY, Wang PY, Lan TH, Fu TF 
Nat Commun. (2015)

著作列表