專任研究人員
tlowary@gate.sinica.edu.tw +886-2-27855696,2050
呂桐睿 特聘研究員 & 所長
中研院生化所 205室

研究領域與專長

Our research program is focused in the areas of synthetic chemistry (with a particular emphasis in carbohydrate chemistry), the conformational analysis of oligosaccharides and the design of novel therapeutic agents that act by inhibiting carbohydrate-processing enzymes. Students and postdoctoral fellows in the group use synthetic chemistry to prepare compounds with interesting biological activities and then have the opportunity to use them in either biochemical or conformational studies.

The primary research focus is directed ultimately towards the identification of new drugs for the treatment of tuberculosis. Our approach is to develop inhibitors of the enzymes that assemble the polysaccharide portions of the protective cell wall of the organism responsible for this disease, Mycobacterium tuberculosis. These polysaccharides are unique in that they are comprised largely of monosaccharides in the furanose ring form. The synthesis of these compounds has been largely neglected by synthetic chemists and our efforts involve both total synthesis and the development of new synthetic methods.

We have completed the total synthesis of a 22-residue oligosaccharide that is an important motif found in the mycobacterial cell wall and fragments of this oligosaccharide, and related analogues, are currently being synthesized and explored in the development of novel vaccines for the prevention of tuberculosis. We are also working towards the characterization of glycosyltransferases involved in mycobacterial cell wall biosynthesis.

學經歷

  • 1993   Ph.D. , Chemistry, University of Alberta
  • 1988   B.A. , Chemistry, University of Montana.
  • 2019 – 迄今   Director, Institute of Biological Chemistry, Academia Sinica
  • 2019 – 迄今   Distinguished Research Fellow, Institute of Biological Chemistry, Academia Sinica
  • 2018 – 2021   Chair, Division of Organic Chemistry, University of Alberta, Department of Chemistry
  • 2015 – 2021   R. U. Lemieux Chair in Carbohydrate Chemistry
  • 2006 – 2021   Professor, University of Alberta
  • 2014 – 2020   Scientific Director, Canadian Glycomics Network (NCE)
  • 2014 – 2019   Canada Research Chair in Carbohydrate Chemistry (Tier 1)
  • 2013 – 2014   Associate Chair, Graduate Studies, University of Alberta, Department of Chemistry
  • 2012 – 2015   Scientific Director, Alberta Glycomics Centre
  • 2009 – 2011   Associate Director, Science, Alberta Glycomics Centre
  • 2009 – 2011   Associate Chair, Graduate Studies, University of Alberta, Department of Chemistry
  • 2006 – 2011   Chair, Division of Organic Chemistry, University of Alberta, Department of Chemistry
  • 2003 – 2006   Associate Professor, University of Alberta
  • 2002 – 2003   Associate Professor, The Ohio State University
  • 1996 – 2002   Assistant Professor, The Ohio State University

主要著作

A Convergent Route to Enantiomers of the Bicyclic Monosaccharide Bradyrhizose Leads to Insight into the Bioactivity of an Immunologically Silent Lipopolysaccharide. 
Aboussafy, C. L.; Andersen Gersby, L. B.; Molinaro, A.; Newman, M.-A.; Lowary, T. L. 
J. Org. Chem. (2019)

Characterization of the Antigenic Heterogeneity of Lipoarabinomannan (LAM), the Major SurfaceGlycolipid of Mycobacterium tuberculosis, and Complexity of Antibody Specificities toward This Antigen. 
Choudhary, A.; Patel, D.; Honnen, W.; Lai, Z.; Prattipati, R.; Zheng, R. B.; Hsueh, Y-C.; Gennaro, M. L.; Lardizabal, A.; Joe, M.; Bai. Y.; Shen, K.; Spencer, J.; Chatterjee, D.; Broger, T.; Lowary, T. L.; Pinter, A. 
J. Immunol. (2018)

Synthesis of the Campylobacter jejuni 81-176 strain capsular polysaccharide repeating unit reveals the absolute configuration of its O-methyl phosphoramidate motif. 
Thota, V. N.; Ferguson, M. J.; Sweeney, R. P.; Lowary, T. L. 
Angew. Chem. Intl. Ed. (2018)

Synthesis of the highly branched hexasaccharide core of chlorella virus N-linked glycans. 
Lin, S.; Lowary, T. L. 
Chem Eur J. (2018)

Insights into mycobacteria interactions with the host innate immune system from a novel array of synthetic mycobacterial glycans. 
Zheng, R.B.; Jégouzo, S. A. F.; Joe, M.; Bai, Y.; Tran, H. A.; Shen, K.; Saupe, J.; Xia, L.; Ahmed, M. F.; Liu, Y.-H.; Patil, P. S.; Tripathi, A.; Hung, S.-C.; Taylor, M. E.; Lowary, T. L.; Drickamer, K. 
ACS Chem. Biol. (2017)

Association of Human Antibodies to Arabinomannan with Enhanced Mycobacterial Opsonophagocytosis and Intracellular Growth Reduction. 
Chen, T.; Blanc, C.; Eder, A. Z.; Prados-Rosales, R.; Oliveira-Souza, A. C.; Kim, R. S.; Glatman-Friedman, A.; Joe, M.; Bai, Y.; Lowary, T. L.; Tanner, R.; Brennan, M. J.; Fletcher, H. A.; McShane, H.; Casadevall, A.; Achkar, J. M. 
J. Infect. Dis. (2016)

Effect of phenolic glycolipids from Mycobacterium kansasii on proinflammatory cytokine release. A structure–activity relationship study. 
Elsaidi, H. R. H.; Lowary, T. L. 
Chem. Sci. (2015)

Synthesis of Carbohydrate Methyl Phosphoramidates. 
Ashmus, R. A.; Lowary, T. L. 
Org. Lett. (2014)

Tetrameric structure of GlfT2 reveals a scaffold for the assembly of mycobacterial arabinogalactan. 
Wheatley, R. W.; Zheng, R. B.; Richards, M. R.; Lowary, T. L.; Ng, K. K. S. 
J. Biol. Chem. (2012)

Synthesis of the Docosanasaccharide Arabinan Domain of Mycobacterial Arabinogalactan and a Proposed Octadecasaccharide Biosynthetic Precursor. 
Joe, M.; Bai, Y.; Nacario, R. C.; Lowary, T. L. 
J. Am. Chem. Soc. (2007)

著作列表

  1. Doyle L, Ovchinnikova OG, Huang BS, Forrester TJB, (Lowary TL), Kimber MS, Whitfield C  (2023-05)  The Journal of biological chemistry  299(5), 104609  "Mechanism and linkage specificities of the dual retaining beta-Kdo glycosyltransferase modules of KpsC from bacterial capsule biosynthesis."
  2. Schmidt EN, Lamprinaki D, McCord KA, Joe M, Sojitra M, Waldow A, Nguyen J, Monyror J, Kitova EN, Mozaneh F, Guo XY, Jung J, Enterina JR, Daskhan GC, Han L, Krysler AR, Cromwell CR, Hubbard BP, West LJ, Kulka M, Sipione S, Klassen JS, Derda R, (Lowary TL), Mahal LK, Riddell MR, Macauley MS  (2023-04)  Nature communications  14(1), 2327  "Siglec-6 mediates the uptake of extracellular vesicles through a noncanonical glycolipid binding pocket."
  3. Frame NW, Allas MJ, Pequegnat B, Vinogradov E, Liao VC, Al-Abdul-Wahid S, Arroyo L, Allen-Vercoe E, (Lowary TL)*, Monteiro MA*  (2023-04)  Carbohydrate research  526, 108805  "Structure and synthesis of a vaccine and diagnostic target for Enterocloster bolteae, an autism-associated gut pathogen - Part II."
  4. Corrigan DT, Ishida E, Chatterjee D, (Lowary TL), Achkar JM*  (2023-01)  Trends in microbiology  31(1), 22-35  "Monoclonal antibodies to lipoarabinomannan/arabinomannan - characteristics and implications for tuberculosis research and diagnostics."
  5. Speciale I, Notaro A, Abergel C, Lanzetta R, (Lowary TL), Molinaro A, Tonetti M, Van Etten JL, De Castro C  (2022-10)  Chemical reviews  122(20), 15717-15766  "The Astounding World of Glycans from Giant Viruses."
  6. Forrester TJB, Ovchinnikova OG, Li Z, Kitova EN, Nothof JT, Koizumi A, Klassen JS, (Lowary TL), Whitfield C, Kimber MS  (2022-10)  Nature communications  13(1), 6277  "The retaining beta-Kdo glycosyltransferase WbbB uses a double-displacement mechanism with an intermediate adduct rearrangement step."
  7. Shen K, (Lowary TL)*  (2022-09)  Organic letters  24(35), 6428-6432  "Synthesis of the Mycobacterium tuberculosis Canetti Lipooligosaccharide II Nonasaccharide."
  8. Yang S, Chu CJ, (Lowary TL)*  (2022-08)  Organic letters  24(30), 5614-5618  "A De Novo Route to 3,6-Dideoxy Sugars."
  9. Kelly SD, Williams DM, Nothof JT, Kim T, (Lowary TL), Kimber MS*, Whitfield C*  (2022-05)  Nature Chemical Biology  18(5), 530-537  "The biosynthetic origin of ribofuranose in bacterial polysaccharides."
  10. Kim T, Bell MR, Thota VN, (Lowary TL)*  (2022-04)  The Journal of organic chemistry  87(7), 4894-4907  "One-Pot Regioselective Diacylation of Pyranoside 1,2-cis Diols."
  11. (Lowary TL)*, Achkar JM*  (2022-03)  The Journal of biological chemistry  298(3), 101678  "Tailor Made: New Insights Into Lipoarabinomannan Structure May Improve TB Diagnosis."
  12. Nguyen L, McCord KA, Bui DT, Bouwman KM., Kitova EN, Elaish M, Kumawat D, Daskhan GC, Tomris I, Han L, Chopra P, Yang TJ, Willows SD, Mason AL, Mahal LK, (Lowary TL), West LJ, Hsu STD, Hobman T, Tompkins SM, Boons GJ, de Vries RP, Macauley MS*, Klassen JS*  (2022-01)  Nature Chemical Biology  18(1), 81-90  "Sialic acid-containing glycolipids mediate binding and viral entry of SARS-CoV-2"
  13. Bentall A, Jeyakanthan M, Braitch M, Cairo CW, (Lowary TL), Maier S, Halpin A, Motyka B, Zou L, West LJ, Ball S  (2021-11)  American Journal of Transplantation  21(11), 3649-3662  "Characterization of ABH-subtype donor-specific antibodies in ABO-A-incompatible kidney transplantation."
  14. Shen K, Bai B, Liu YH, (Lowary TL)*  (2021-11)  Angewandte Chemie - International Edition  60(47), 24859-24863  "Synthesis of a Tridecasaccharide Lipooligosaccharide Antigen from the Opportunistic Pathogen Mycobacterium kansasii."
  15. Anso I, Basso LGM, Wang L, Marina A, Paez-Perez ED, Jager C, Gavotto F, Tersa M, Perrone S, Contreras FX, Prandi J, Gilleron M, Linster CL, Corzana F, (Lowary TL), Trastoy B, Guerin ME  (2021-10)  Science advances  7(42), eabj4565  "Molecular ruler mechanism and interfacial catalysis of the integral membrane acyltransferase PatA."
  16. Ishida E, Corrigan DT, Malonis RJ, Hofmann D, Chen T, Amin AG, Chatterjee D, Joe M, (Lowary TL), Lai JR, Achkar JM  (2021-10)  Communications biology  4(1), 1181  "Monoclonal antibodies from humans with Mycobacterium tuberculosis exposure or latent infection recognize distinct arabinomannan epitopes."
  17. Wang L, (Lowary TL)*  (2021-09)  Chemical Science  12(36), 12192-12200  "Synthesis of structurally-defined polymeric glycosylated phosphoprenols as potential lipopolysaccharide biosynthetic probes"
  18. Sojitra M, Sarkar S, Maghera J, Rodrigues E, Carpenter EJ, Seth S, Ferrer Vinals D, Bennett NJ, Reddy R, Khalil A, Xue X, Bell MR, Zheng RB, Zhang P, Nycholat C, Bailey JJ, Ling CC, (Lowary TL), Paulson JC, Macauley MS, Derda R.  (2021-07)  Nature Chemical Biology  17(7), 806-816  "Genetically encoded multivalent liquid glycan array displayed on M13 bacteriophage"
  19. Tcheng M, Cunha VLS, Ahmed N, Liu X, Smith RW, Rea KA, Akhtar TA, D'Alessandro A, Minden MD, Vockley J, O'Doherty GA, (Lowary TL), Spagnuolo PA  (2021-07)  Food & function  12(14), 6323-6333  "Structure-activity relationship of avocadyne."
  20. Liang XY, Yang J, Qiu ZH, Wang L, (Lowary TL), Shawn Fan HJ  (2021-02)  Carbohydrate Research  500, 108237  "4,6-Di-O-Benzylidenyl group-directed preparation of 2-deoxy-2-azido-α-d-galactopyranosides promoted by 3-O-TBDPS."
  21. Angala SK, Joe M, McNeil MR, Liav A, (Lowary TL), Jackson M  (2021-01)  ACS Chem Biol.  16(1), 20-26  "Use of Synthetic Glycolipids to Probe the Number and Position of Arabinan Chains on Mycobacterial Arabinogalactan."
  22. Huang BS, (Lowary TL)*  (2020-12)  The Journal of organic chemistry  85(24), 15895-15907  "A Siloxane-Bridged Glycosyl Donor Enables Highly Stereoselective beta-Xylulofuranosylation."
  23. (Lowary TL), Pohl NL  (2020-12)  J Org Chem.  85(24), 15778-15779  "A Very Short History of the Carbohydrate Division of the American Chemical Society."
  24. Wang L, (Lowary TL)*  (2020-12)  Org Lett.  22(24), 9633-9637  "Synthesis of Rhamnolipid Derivatives Containing Ester Isosteres."
  25. Speciale I, Laugieri ME, Noel E, Lin S, (Lowary TL), Molinaro A, Duncan GA, Agarkova IV, Garozzo D, Tonetti MG, Van Etten JL, De Castro C  (2020-11)  Proceedings of the National Academy of Sciences of the United States of America  117(46), 28735-28742  "Chlorovirus PBCV-1 protein A064R has three of the transferase activities necessary to synthesize its capsid protein N-linked glycans."
  26. Broger T, Nicol M, Sigal G, Gotuzzo E, Zimmer AJ, Surtie S, Caceres-Nakiche T, Mantsoki A, Reipold EI, Szekely R, Tsionsky M, van Heerden J, Plisova T, Chikamatsu K, (Lowary TL), Pinter A, Mitarai S, Moreau E, Schumacher SG, Denkinger CM  (2020-11)  The Journal of clinical investigation  130(11), 5756-5764  "Diagnostic accuracy of three urine lipoarabinomannan tuberculosis assays in HIV-negative outpatients."
  27. Han L, Xue X, Roy R, Kitova EN, Zheng RB, St-Pierre Y, (Lowary TL), Klassen JS  (2020-10)  Anal. Chem.  92(20), 14189-14196  "Neoglycolipids as Glycosphingolipid Surrogates for Protein Binding Studies Using Nanodiscs and Native Mass Spectrometry"
  28. Lin S, (Lowary TL)  (2020-10)  Org. Lett.  22(19), 7645-7649  "Synthesis of a Highly Branched Nonasaccharide Chlorella Virus N-Glycan Using a "Counterclockwise" Assembly Approach"
  29. Tan YZ, Rodrigues J, Keener JE, Zheng RB, Brunton R, Kloss B, Giacometti SI, Rosario AL, Zhang L, Niederweis M, Clarke OB, (Lowary TL), Marty MT, Archer M, Potter CS, Carragher B, Mancia F  (2020-07)  Nature communications  11(1), 3396  "Cryo-EM structure of arabinosyltransferase EmbB from Mycobacterium smegmatis."
  30. Tan YZ, Zhang L, Rodrigues J, Zheng RB, Giacometti SI, Rosario AL, Kloss B, Dandey VP, Wei H, Brunton R, Raczkowski AM, Athayde D, Catalao MJ, Pimentel M, Clarke OB, (Lowary TL), Archer M, Niederweis M, Potter CS, Carragher B, Mancia F  (2020-05)  Molecular cell  78(4), 683-699.e11  "Cryo-EM Structures and Regulation of Arabinofuranosyltransferase AftD from Mycobacteria."
  31. Clarke BR, Ovchinnikova OG, Sweeney RP, Kamski-Hennekam ER, Gitalis R, Mallette E, Kelly SD, (Lowary TL), Kimber MS, Whitfield C  (2020-04)  Nature chemical biology  16(4), 450-457  "A bifunctional O-antigen polymerase structure reveals a new glycosyltransferase family."
  32. Chen T, Blanc C, Liu Y, Ishida E, Singer S, Xu J, Joe M, Jenny-Avital ER, Chan J, (Lowary TL), Achkar JM  (2020-04)  The Journal of clinical investigation  130(4), 1808-1822  "Capsular glycan recognition provides antibody-mediated immunity against tuberculosis."
  33. Shen L, Viljoen A, Villaume S, Joe M, Halloum I, Chene LP, Mery A, Fabre E, Takegawa K, (Lowary TL), Vincent SP, Kremer L, Guerardel Y, Mariller C  (2020-04)  The Journal of biological chemistry  295(15), 5110-5123  "The endogenous galactofuranosidase GlfH1 hydrolyzes mycobacterial arabinogalactan."
  34. Huang BS, (Lowary TL)*  (2020-03)  Organic & biomolecular chemistry  18(12), 2264-2273  "beta-Selective xylulofuranosylation via a conformationally-restricted glycosyl donor."
  35. Angala SK, Li W, Palcekova Z, Zou L, (Lowary TL), McNeil MR, Jackson M  (2019-12)  International journal of molecular sciences  20(24), E6244  "Cloning and Partial Characterization of an Endo-alpha-(1-->6)-d-Mannanase Gene from Bacillus circulans."
  36. Cunha VLS, Liu X, (Lowary TL), O'Doherty GA  (2019-12)  The Journal of organic chemistry  84(23), 15718-15725  "De Novo Asymmetric Synthesis of Avocadyne, Avocadene, and Avocadane Stereoisomers."
  37. Sweeney RP, (Lowary TL)  (2019-12)  Current opinion in chemical biology  53, 37-43  "New insights into lipopolysaccharide assembly and export."
  38. Broger T, Sossen B, du Toit E, Kerkhoff AD, Schutz C, Ivanova Reipold E, Ward A, Barr DA, Mace A, Trollip A, Burton R, Ongarello S, Pinter A, (Lowary TL), Boehme C, Nicol MP, Meintjes G, Denkinger CM*  (2019-08)  The Lancet Infectious Diseases  19(8), 852-861  "Novel lipoarabinomannan point-of-care tuberculosis test for people with HIV: a diagnostic accuracy study."
  39. Kelly SD, Clarke BR, Ovchinnikova OG, Sweeney RP, Williamson ML, (Lowary TL), Whitfield C*  (2019-07)  The Journal of biological chemistry  294(28), 10863-10876  "Klebsiella pneumoniae O1 and O2ac antigens provide prototypes for an unusual strategy for polysaccharide antigen diversification."
  40. Doyle L, Ovchinnikova OG, Myler K, Mallette E, Huang BS, (Lowary TL), Kimber MS*, Whitfield C*  (2019-06)  Nature chemical biology  15(6), 632-640  "Biosynthesis of a conserved glycolipid anchor for Gram-negative bacterial capsules."
  41. Palcekova Z, Angala SK, Belardinelli JM, Eskandarian HA, Joe M, Brunton R, Rithner C, Jones V, Nigou J, (Lowary TL), Gilleron M, McNeil M, Jackson M  (2019-06)  The Journal of biological chemistry  294(26), 10325-10335  "Disruption of the SucT acyltransferase in Mycobacterium smegmatis abrogates succinylation of cell envelope polysaccharides."
  42. Broger T, Tsionksy M, Mathew A, (Lowary TL), Pinter A, Plisova T, Bartlett D, Barbero S, Denkinger CM, Moreau E, Katsuragi K, Kawasaki M, Nahid P, Sigal GB  (2019-04)  PloS one  14(4), e0215443  "Sensitive electrochemiluminescence (ECL) immunoassays for detecting lipoarabinomannan (LAM) and ESAT-6 in urine and serum from tuberculosis patients."
  43. Speciale I, Duncan GA, Unione L, Agarkova IV, Garozzo D, Jimenez-Barbero J, Lin S, (Lowary TL), Molinaro A, Noel E, Laugieri ME, Tonetti MG, Van Etten JL, De Castro C  (2019-04)  The Journal of biological chemistry  294(14), 5688-5699  "The N-glycan structures of the antigenic variants of chlorovirus PBCV-1 major capsid protein help to identify the virus-encoded glycosyltransferases."
  44. Sweeney RP, (Lowary TL)*  (2019-02)  Organic letters  21(4), 1050-1053  "A Route to Polyprenol Pyrophosphate-Based Probes of O-Polysaccharide Biosynthesis in Klebsiella pneumoniae O2a."
  45. Gao Z, Ovchinnikova OG, Huang BS, Liu F, Williams DE, Andersen RJ, (Lowary TL), Whitfield C, Withers SG*  (2019-02)  Journal of the American Chemical Society  141(6), 2201-2204  "High-Throughput "FP-Tag" Assay for the Identification of Glycosyltransferase Inhibitors."
  46. Aboussafy CL, Andersen Gersby LB, Molinaro A, Newman MA, (Lowary TL)*  (2019-01)  The Journal of organic chemistry  84(1), 14-41  "A Convergent Route to Enantiomers of the Bicyclic Monosaccharide Bradyrhizose Leads to Insight into the Bioactivity of an Immunologically Silent Lipopolysaccharide."
  47. Ati J, Colas C, Lafite P, Sweeney RP, Zheng RB, (Lowary TL), Daniellou R*  (2018-12)  Scientific reports  8(1), 17566  "The LPG1x family from Leishmania major is constituted of rare eukaryotic galactofuranosyltransferases with unprecedented catalytic properties."
  48. Sigal GB, Pinter A, (Lowary TL), Kawasaki M, Li A, Mathew A, Tsionsky M, Zheng RB, Plisova T, Shen K, Katsuragi K, Choudhary A, Honnen WJ, Nahid P, Denkinger CM, Broger T*  (2018-11)  Journal of clinical microbiology  56(12), e01338-18  "A Novel Sensitive Immunoassay Targeting the 5-Methylthio-d-Xylofuranose-Lipoarabinomannan Epitope Meets the WHO's Performance Target for Tuberculosis Diagnosis."
  49. Thota VN, Ferguson MJ, Sweeney RP, (Lowary TL)*  (2018-11)  Angewandte Chemie International Edition  57(47), 15592-15596  "Synthesis of the Campylobacter jejuni 81-176 Strain Capsular Polysaccharide Repeating Unit Reveals the Absolute Configuration of its O-Methyl Phosphoramidate Motif."
  50. Lin S, (Lowary TL)*  (2018-11)  Chemistry-A European Journal  24(64), 16992-16996  "Synthesis of the Highly Branched Hexasaccharide Core of Chlorella Virus N-Linked Glycans."
  51. Zhang L, Shen K, Taha HA, (Lowary TL)*  (2018-08)  The Journal of organic chemistry  83(15), 7659-7671  "Stereocontrolled Synthesis of alpha-Xylofuranosides Using a Conformationally Restricted Donor."
  52. Amin AG, De P, Spencer JS, Brennan PJ, Daum J, Andre BG, Joe M, Bai Y, Laurentius L, Porter MD, Honnen WJ, Choudhary A, (Lowary TL), Pinter A, Chatterjee D*  (2018-07)  Tuberculosis  111, 178-187  "Detection of lipoarabinomannan in urine and serum of HIV-positive and HIV-negative TB suspects using an improved capture-enzyme linked immuno absorbent assay and gas chromatography/mass spectrometry."
  53. Jankute M, Alderwick LJ, Moorey AR, Joe M, Gurcha SS, Eggeling L, (Lowary TL), Dell A, Pang PC, Yang T, Haslam S, Besra GS  (2018-06)  Cell surface  2, 38-53  "The singular Corynebacterium glutamicum Emb arabinofuranosyltransferase polymerises the alpha(1-->5) arabinan backbone in the early stages of cell wall arabinan biosynthesis."
  54. Cocaud C, Zheng RB, (Lowary TL), Poisson T, Pannecoucke X, Nicolas C, Martin OR*  (2018-05)  Carbohydrate research  461, 45-50  "1-C-phosphonomethyl- and 1-C-difluorophosphonomethyl-1,4-imino-l-arabinitols as Galf transferase inhibitors: A comparison."
  55. Choudhary A, Patel D, Honnen W, Lai Z, Prattipati RS, Zheng RB, Hsueh YC, Gennaro ML, Lardizabal A, Restrepo BI, Garcia-Viveros M, Joe M, Bai Y, Shen K, Sahloul K, Spencer JS, Chatterjee D, Broger T, (Lowary TL), Pinter A*  (2018-05)  Journal of immunology  200(9), 3053-3066  "Characterization of the Antigenic Heterogeneity of Lipoarabinomannan, the Major Surface Glycolipid of Mycobacterium tuberculosis, and Complexity of Antibody Specificities toward This Antigen."
  56. Yang DM, Chen Y, Sweeney RP, (Lowary TL), Liang XY*  (2018-04)  Organic letters  20(8), 2287-2290  "Stereocontrolled Synthesis of 2-Deoxy-galactopyranosides via Isopropylidene-Protected 6- O-Silylated Donors."
  57. Clarke BR, Ovchinnikova OG, Kelly SD, Williamson ML, Butler JE, Liu B, Wang L, Gou X, Follador R, (Lowary TL), Whitfield C*  (2018-03)  The Journal of biological chemistry  293(13), 4666-4679  "Molecular basis for the structural diversity in serogroup O2-antigen polysaccharides in Klebsiella pneumoniae."
  58. Xue X, Zheng RB, Koizumi A, Han L, Klassen JS, (Lowary TL)*  (2018-03)  Organic & biomolecular chemistry  16(11), 1939-1957  "Synthetic polyprenol-pyrophosphate linked oligosaccharides are efficient substrates for mycobacterial galactan biosynthetic enzymes."
  59. Daskhan GC, Tran HT, Meloncelli PJ, (Lowary TL), West LJ, Cairo CW*  (2018-02)  Bioconjugate chemistry  29(2), 343-362  "Construction of Multivalent Homo- and Heterofunctional ABO Blood Group Glycoconjugates Using a Trifunctional Linker Strategy."
  60. Chou Y, Kitova E, Joe M, Brunton RM, (Lowary TL), Klassen JS, Derda R*  (2018-01)  Organic & Biomolecular Chemistry  16(2), 223-227  "Genetically-encoded fragment-based discovery (GE-FBD) of glycopeptide ligands for antibodies related to mycobacterial infections"
  61. Zheng RB, Jegouzo SAF, Joe M, Bai Y, Tran HA, Shen K, Saupe J, Xia L, Ahmed MF, Liu YH, Patil PS, Tripathi A, Hung SC, Taylor ME*, (Lowary TL)*, Drickamer K*  (2017-12)  ACS chemical biology  12(12), 2990-3002  "Insights into Interactions of Mycobacteria with the Host Innate Immune System from a Novel Array of Synthetic Mycobacterial Glycans."
  62. Cocaud C, Maujoin A, Rodrigues N, Zheng RB, Buron F, Routier S, (Lowary TL), Nicolas C*, Martin OR*  (2017-11)  Eur. J. Org. Chem.  2017(41), 6192–6201  "Triazole‐Linked Iminosugars and Aromatic Systems as Simplified UDP‐Galf Mimics: Synthesis and Preliminary Evaluation as Galf‐Transferase Inhibitors"
  63. Fiege B, Leuthold M, Parra F, Dalton KP, Meloncelli PJ, (Lowary TL), Peters T*  (2017-10)  Glycoconjugate journal  34(5), 679-689  "Epitope mapping of histo blood group antigens bound to norovirus VLPs using STD NMR experiments reveals fine details of molecular recognition."
  64. Angala SK, McNeil MR, Shi L, Joe M, Pham H, Zuberogoitia S, Nigou J, Boot CM, (Lowary TL), Gilleron M, Jackson M  (2017-03)  ACS chemical biology  12(3), 682-691  "Biosynthesis of the Methylthioxylose Capping Motif of Lipoarabinomannan in Mycobacterium tuberculosis."
  65. Prados-Rosales R, Carreno L, Cheng T, Blanc C, Weinrick B, Malek A, (Lowary TL), Baena A, Joe M, Bai Y, Kalscheuer R, Batista-Gonzalez A, Saavedra NA, Sampedro L, Tomas J, Anguita J, Hung SC, Tripathi A, Xu J, Glatman-Freedman A, Jacobs WR Jr, Chan J, Porcelli SA, Achkar JM, Casadevall A  (2017-03)  PLoS pathogens  13(3), e1006250  "Enhanced control of Mycobacterium tuberculosis extrapulmonary dissemination in mice by an arabinomannan-protein conjugate vaccine."
  66. Williams DM, Ovchinnikova OG, Koizumi A, Mainprize IL, Kimber MS, (Lowary TL), Whitfield C  (2017-02)  Proceedings of the National Academy of Sciences of the United States of America  114(7), E1215-E1223  "Single polysaccharide assembly protein that integrates polymerization, termination, and chain-length quality control."
  67. Joe M, (Lowary TL)*  (2016-11)  Canadian Journal of Chemistry  94(11): 976-988  "Synthesis of a homologous series of galactofuranose-containing mycobacterial arabinogalactan fragments"
  68. Ovchinnikova OG, Doyle L, Huang BS, Kimber MS, (Lowary TL), Whitfield C  (2016-10)  The Journal of biological chemistry  291(41), 21519-21530  "Biochemical Characterization of Bifunctional 3-Deoxy-beta-d-manno-oct-2-ulosonic Acid (beta-Kdo) Transferase KpsC from Escherichia coli Involved in Capsule Biosynthesis."
  69. Frederic CJ, Tikad A, Fu J, Pan W, Zheng RB, Koizumi A, Xue X, (Lowary TL), Vincent SP*  (2016-10)  CHEMISTRY-A EUROPEAN JOURNAL  22(44), 15913-15920  "Synthesis of Unprecedented Sulfonylated Phosphono-exo-Glycals Designed as Inhibitors of the Three Mycobacterial Galactofuranose Processing Enzymes."
  70. Poulin MB, (Lowary TL)*  (2016-09)  The Journal of organic chemistry  81(18), 8123-8130  "Chemical Insight into the Mechanism and Specificity of GlfT2, a Bifunctional Galactofuranosyltransferase from Mycobacteria."
  71. Harrison J, Lloyd G, Joe M, (Lowary TL), Reynolds E, Walters-Morgan H, Bhatt A, Lovering A, Besra GS, Alderwick LJ*  (2016-08)  mBio  7(4), e00972-16  "Lcp1 Is a Phosphotransferase Responsible for Ligating Arabinogalactan to Peptidoglycan in Mycobacterium tuberculosis."
  72. Liu L, Siuda I, Richards MR, Renaud J, Kitova EN, Mayer PM, Tieleman DP, (Lowary TL), Klassen JS*  (2016-08)  Chembiochem : a European journal of chemical biology  17(16), 1571-1578  "Structure and Stability of Carbohydrate-Lipid Interactions. Methylmannose Polysaccharide-Fatty Acid Complexes."
  73. (Lowary TL), Li J*  (2016-08)  Molecules  21(8), E1053  "Synthesis and Evaluation of Bicyclo[3.1.0]hexane-Based UDP-Galf Analogues as Inhibitors of the Mycobacterial Galactofuranosyltransferase GlfT2."
  74. Chen T, Blanc C, Eder AZ, Prados-Rosales R, Souza AC, Kim RS, Glatman-Freedman A, Joe M, Bai Y, (Lowary TL), Tanner R, Brennan MJ, Fletcher HA, McShane H, Casadevall A, Achkar JM*  (2016-07)  The Journal of infectious diseases  214(2), 300-310  "Association of Human Antibodies to Arabinomannan With Enhanced Mycobacterial Opsonophagocytosis and Intracellular Growth Reduction."
  75. (Lowary TL)*  (2016-07)  Accounts of chemical research  49(7), 1379-1388  "Twenty Years of Mycobacterial Glycans: Furanosides and Beyond."
  76. Angala SK, McNeil MR, Zou L, Liav A, Zhang J, (Lowary TL), Jackson M*  (2016-06)  ACS chemical biology  11(6), 1518-1524  "Identification of a Novel Mycobacterial Arabinosyltransferase Activity Which Adds an Arabinosyl Residue to alpha-d-Mannosyl Residues."
  77. Jeyakanthan M, Meloncelli PJ, Zou L, (Lowary TL), Larsen I, Maier S, Tao K, Rusch J, Chinnock R, Shaw N, Burch M, Beddows K, Addonizio L, Zuckerman W, Pahl E, Rutledge J, Kanter KR, Cairo CW, Buriak JM, Ross D, Rebeyka I, West LJ*  (2016-05)  American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons  16(5), 1548-1558  "ABH-Glycan Microarray Characterizes ABO Subtype Antibodies: Fine Specificity of Immune Tolerance After ABO-Incompatible Transplantation."
  78. Lin S, Ashmus RA, (Lowary TL)*  (2016-05)  Eur. J. Org. Chem.  2016(15), 2653–2664  "An Oxidation–Amidation Approach for the Synthesis of Glycuronamides"
  79. Ovchinnikova OG, Mallette E, Koizumi A, (Lowary TL), Kimber MS*, Whitfield C*  (2016-05)  Proceedings of the National Academy of Sciences of the United States of America  113(22), E3120-3129  "Bacterial beta-Kdo glycosyltransferases represent a new glycosyltransferase family (GT99)."
  80. Ashmus RA, Jayasuriya AB, Lim YJ, O'Doherty GA, (Lowary TL)*  (2016-04)  The Journal of organic chemistry  81(7), 3058-3063  "De Novo Asymmetric Synthesis of a 6-O-Methyl-D-glycero-L-gluco-heptopyranose-Derived Thioglycoside for the Preparation of Campylobacter jejuni NCTC11168 Capsular Polysaccharide Fragments."
  81. Slaney AM, Dijke IE, Jeyakanthan M, Li C, Zou L, Plaza-Alexander P, Meloncelli PJ, Bau JA, Allan LL, (Lowary TL), West LJ, Cairo CW, Buriak JM*  (2016-03)  Bioconjugate chemistry  27(3), 705-715  "Conjugation of A and B Blood Group Structures to Silica Microparticles for the Detection of Antigen-Specific B Cells."
  82. Schieck E, Lartigue C, Frey J, Vozza N, Hegermann J, Miller RA, Valguarnera E, Muriuki C, Meens J, Nene V, Naessens J, Weber J, (Lowary TL), Vashee S, Feldman MF, Jores J*  (2016-01)  Molecular microbiology  99(1), 55-70  "Galactofuranose in Mycoplasma mycoides is important for membrane integrity and conceals adhesins but does not contribute to serum resistance."
  83. Sahloul K, (Lowary TL)*  (2015-11)  The Journal of organic chemistry  80(22), 11417-11434  "Development of an Orthogonal Protection Strategy for the Synthesis of Mycobacterial Arabinomannan Fragments."
  84. Gagnon SM, Meloncelli PJ, Zheng RB, Haji-Ghassemi O, Johal AR, Borisova SN, (Lowary TL), Evans SV*  (2015-11)  The Journal of biological chemistry  290(45), 27040-27052  "High Resolution Structures of the Human ABO(H) Blood Group Enzymes in Complex with Donor Analogs Reveal That the Enzymes Utilize Multiple Donor Conformations to Bind Substrates in a Stepwise Manner."
  85. Jeyakanthan M, Tao K, Zou L, Meloncelli PJ, (Lowary TL), Suzuki K, Boland D, Larsen I, Burch M, Shaw N, Beddows K, Addonizio L, Zuckerman W, Afzali B, Kim DH, Mengel M, Shapiro AM, West LJ  (2015-10)  American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons  15(10), 2602-2615  "Chemical Basis for Qualitative and Quantitative Differences Between ABO Blood Groups and Subgroups: Implications for Organ Transplantation."
  86. Conde P, Rodriguez M, van der Touw W, Jimenez A, Burns M, Miller J, Brahmachary M, Chen HM, Boros P, Rausell-Palamos F, Yun TJ, Riquelme P, Rastrojo A, Aguado B, Stein-Streilein J, Tanaka M, Zhou L, Zhang J, (Lowary TL), Ginhoux F, Park CG, Cheong C, Brody J, Turley SJ, Lira SA, Bronte V, Gordon S, Heeger PS, Merad M, Hutchinson J, Chen SH, Ochando J  (2015-06)  Immunity  42(6), 1143-1158  "DC-SIGN(+) Macrophages Control the Induction of Transplantation Tolerance."
  87. Elsaidi HRH, (Lowary TL)*  (2015-05)  Chemical science  6(5), 3161-3172  "Effect of phenolic glycolipids from Mycobacterium kansasii on proinflammatory cytokine release. A structure-activity relationship study."
  88. Bai B, Chu CJ, (Lowary TL)*  (2015-04)  Isr. J. Chem.  55(3-4), 360–372  "Lipooligosaccharides from Mycobacteria: Structure, Function, and Synthesis"
  89. Wang L, Dong M, (Lowary TL)*  (2015-03)  The Journal of organic chemistry  80(5), 2767-2780  "Synthesis of unusual N-acylated aminosugar fragments of Mycobacterium marinum lipooligosaccharide IV."
  90. Poopari MR, Dezhahang Z, Shen K, Wang L, (Lowary TL), Xu Y*  (2015-01)  The Journal of organic chemistry  80(1), 428-437  "Absolute Configuration and Conformation of Two Frater-Seebach Alkylation Reaction Products by Film VCD and ECD Spectroscopic Analyses."
  91. Liston SD, Clarke BR, Greenfield LK, Richards MR, (Lowary TL), Whitfield C*  (2015-01)  The Journal of biological chemistry  290(2), 1075-1085  "Domain interactions control complex formation and polymerase specificity in the biosynthesis of the Escherichia coli O9a antigen."
  92. Lak P, Makeneni S, Woods RJ, (Lowary TL)*  (2015-01)  CHEMISTRY-A EUROPEAN JOURNAL  21(3), 1138-1148  "Specificity of furanoside-protein recognition through antibody engineering and molecular modeling."
  93. Zhang D, Huang P, Zou L, (Lowary TL), Tan M, Jiang X*  (2015-01)  Journal of virology  89(2), 1419-1427  "Tulane virus recognizes the A type 3 and B histo-blood group antigens."
  94. Arutyunov D, Singh U, El-Hawiet A, Seckler HD, Nikjah S, Joe M, Bai Y, (Lowary TL), Klassen JS, Evoy S*, Szymanski CM*  (2014-12)  Bacteriophage  4(4), e960346  "Mycobacteriophage cell binding proteins for the capture of mycobacteria."
  95. Backus KM, Dolan MA, Barry CS, Joe M, McPhie P, Boshoff HI, (Lowary TL), Davis BG, Barry CE 3rd*  (2014-09)  The Journal of biological chemistry  289(36), 25041-25053  "The three Mycobacterium tuberculosis antigen 85 isoforms have unique substrates and activities determined by non-active site regions."
  96. Elsaidi HR, (Lowary TL)*  (2014-05)  Chembiochem  15(8), 1176-1182  "Inhibition of cytokine release by mycobacterium tuberculosis phenolic glycolipid analogues."
  97. Ashmus RA, (Lowary TL)*  (2014-05)  Organic letters  16(9), 2518-2521  "Synthesis of carbohydrate methyl phosphoramidates."
  98. van Alphen LB, Wenzel CQ, Richards MR, Fodor C, Ashmus RA, Stahl M, Karlyshev AV, Wren BW, Stintzi A, Miller WG, (Lowary TL), Szymanski CM*  (2014-01)  PloS one  9(1), e87051  "Biological roles of the O-methyl phosphoramidate capsule modification in Campylobacter jejuni."
  99. Poulin MB, Shi Y, Protsko C, Dalrymple SA, Sanders DA, Pinto BM, (Lowary TL)*  (2014-01)  Chembiochem : a European journal of chemical biology  15(1), 47-56  "Specificity of a UDP-GalNAc pyranose-furanose mutase: a potential therapeutic target for Campylobacter jejuni infections."
  100. Snitynsky RB, (Lowary TL)*  (2014-01)  Organic letters  16(1), 212-215  "Synthesis of nitrogen-containing furanose sugar nucleotides for use as enzymatic probes."
  101. Li J, (Lowary TL)*  (2014)  MedChemComm  5, 1130-1137  "Sulfonium ions as inhibitors of the mycobacterial galactofuranosyltransferase GlfT2"
  102. Zhai Y, Dasog M, Snitynsky RB, Purkait TK, Aghajamali M, Hahn AH, Sturdy CB, (Lowary TL), Veinot JGC*  (2014)  J. Mater. Chem. B  2, 8427-8433  "Water-Soluble Photoluminescent D-Mannose and L-Alanine Functionalized Silicon Nanocrystals and Their Application to Cancer Cell Imaging"
  103. (Lowary TL)*  (2013-12)  Current opinion in chemical biology  17(6), 990-996  "Context and complexity: the next big thing in synthetic glycobiology."
  104. Elsaidi HR, Barreda DR, Cairo CW, (Lowary TL)*  (2013-11)  Chembiochem : a European journal of chemical biology  14(16), 2153-2159  "Mycobacterial phenolic glycolipids with a simplified lipid aglycone modulate cytokine levels through Toll-like receptor 2."
  105. Xia L, (Lowary TL)*  (2013-10)  Biopolymers  99(10), 697-712  "Amphiphilic cytosolic glycans from mycobacteria: occurrence, lipid-binding properties, biosynthesis, and synthesis."
  106. Zhang J, Zou L, (Lowary TL)*  (2013-08)  ChemistryOpen  2(4), 156-163  "Synthesis of the Tolerance-Inducing Oligosaccharide Lacto-N-Fucopentaose III Bearing an Activated Linker."
  107. Richards MR, Bai Y, (Lowary TL)*  (2013-06)  Carbohydrate research  374, 103-114  "Comparison between DFT- and NMR-based conformational analysis of methyl galactofuranosides."
  108. Willis LM, Stupak J, Richards MR, (Lowary TL), Li J, Whitfield C*  (2013-05)  Proceedings of the National Academy of Sciences of the United States of America  110(19), 7868-7873  "Conserved glycolipid termini in capsular polysaccharides synthesized by ATP-binding cassette transporter-dependent pathways in Gram-negative pathogens."
  109. Ahmed MF, (Lowary TL)*  (2013-05)  Tetrahedron  69(21), 4276–4284  "Glycosylations with 2,3-aziridinofuranose derivatives"
  110. Xia L, (Lowary TL)*  (2013-04)  The Journal of organic chemistry  78(7), 2863-2880  "Regioselective polymethylation of alpha-(1 --> 4)-linked mannopyranose oligosaccharides."
  111. Taha HA, Richards MR, (Lowary TL)*  (2013-03)  Chemical reviews  113(3), 1851-1876  "Conformational analysis of furanoside-containing mono- and oligosaccharides."
  112. Plaza-Alexander P, (Lowary TL)*  (2013)  ARKIVOC  2013(2), 112–122  "Synthesis of trisaccharides incorporating the α-Gal antigen functionalized for neoglycoconjugate preparation"
  113. Greenfield LK, Richards MR, Vinogradov E, Wakarchuk WW, (Lowary TL), Whitfield C*  (2012-11)  The Journal of biological chemistry  287(45), 38135-38149  "Domain organization of the polymerizing mannosyltransferases involved in synthesis of the Escherichia coli O8 and O9a lipopolysaccharide O-antigens."
  114. Peng W, Zou L, Bhamidi S, McNeil MR, (Lowary TL)*  (2012-11)  The Journal of organic chemistry  77(21), 9826-9832  "The galactosamine residue in mycobacterial arabinogalactan is alpha-linked."
  115. Greenfield LK, Richards MR, Li J, Wakarchuk WW, (Lowary TL), Whitfield C*  (2012-10)  The Journal of biological chemistry  287(42), 35078-35091  "Biosynthesis of the polymannose lipopolysaccharide O-antigens from Escherichia coli serotypes O8 and O9a requires a unique combination of single- and multiple-active site mannosyltransferases."
  116. Liu L, Bai Y, Sun N, Xia L, (Lowary TL)*, Klassen JS*  (2012-09)  CHEMISTRY-A EUROPEAN JOURNAL  18(38), 12059-12067  "Carbohydrate-lipid interactions: affinities of methylmannose polysaccharides for lipids in aqueous solution."
  117. Wheatley RW, Zheng RB, Richards MR, (Lowary TL)*, Ng KK*  (2012-08)  The Journal of biological chemistry  287(33), 28132-28143  "Tetrameric structure of the GlfT2 galactofuranosyltransferase reveals a scaffold for the assembly of mycobacterial Arabinogalactan."
  118. Xia L, Zheng RB, (Lowary TL)*  (2012-05)  Chembiochem : a European journal of chemical biology  13(8), 1139-1151  "Revisiting the specificity of an alpha-(1-->4)-mannosyltransferase involved in mycobacterial methylmannose polysaccharide biosynthesis."
  119. Poulin MB, Zhou R, (Lowary TL)*  (2012-05)  Organic & biomolecular chemistry  10(20), 4074-4087  "Synthetic UDP-galactofuranose analogs reveal critical enzyme-substrate interactions in GlfT2-catalyzed mycobacterial galactan assembly."
  120. Sarkar S, Tang XL, Das D, Spencer JS, (Lowary TL), Suresh MR*  (2012)  PloS one  7(2), e32340  "A bispecific antibody based assay shows potential for detecting tuberculosis in resource constrained laboratory settings."
  121. Zou L, Zheng RB, (Lowary TL)*  (2012)  Beilstein journal of organic chemistry  8, 1219-1226  "Studies on the substrate specificity of a GDP-mannose pyrophosphorylase from Salmonella enterica."
  122. Clarke BR, Richards MR, Greenfield LK, Hou D, (Lowary TL), Whitfield C*  (2011-12)  The Journal of biological chemistry  286(48), 41391-41401  "In vitro reconstruction of the chain termination reaction in biosynthesis of the Escherichia coli O9a O-polysaccharide: the chain-length regulator, WbdD, catalyzes the addition of methyl phosphate to the non-reducing terminus of the growing glycan."
  123. Peng W, Jayasuriya AB, Imamura A, (Lowary TL)*  (2011-10)  Organic letters  13(19), 5290-5293  "Synthesis of the 6-O-methyl-D-glycero-alpha-L-gluco-heptopyranose moiety present in the capsular polysaccharide from Campylobacter jejuni NCTC 11168."
  124. Islam SM, Richards MR, Taha HA, Byrns SC, (Lowary TL), Roy PN*  (2011-09)  Journal of chemical theory and computation  7(9), 2989-3000  "Conformational Analysis of Oligoarabinofuranosides: Overcoming Torsional Barriers with Umbrella Sampling."
  125. Meloncelli PJ, West LJ, (Lowary TL)*  (2011-09)  Carbohydrate research  346(12), 1406-1426  "Synthesis and NMR studies on the ABO histo-blood group antigens: synthesis of type III and IV structures and NMR characterization of type I-VI antigens."
  126. Higgins MA, Ficko-Blean E, Meloncelli PJ, (Lowary TL), Boraston AB*  (2011-09)  Journal of molecular biology  411(5), 1017-1036  "The overall architecture and receptor binding of pneumococcal carbohydrate-antigen-hydrolyzing enzymes."
  127. Slaney AM, Wright VA, Meloncelli PJ, Harris KD, West LJ, (Lowary TL)*, Buriak JM*  (2011-05)  ACS applied materials & interfaces  3(5), 1601-1612  "Biocompatible carbohydrate-functionalized stainless steel surfaces: a new method for passivating biomedical implants."
  128. Shi W, (Lowary TL)*  (2011-05)  Bioorganic & medicinal chemistry letters  21(9), 2591-2596  "Effect of carbohydrate amino group modifications on the cytotoxicity of glycosylated 2-phenyl-benzo[b]thiophenes and 2-phenyl-benzo[b]furans."
  129. Frigell J, Pearcey JA, (Lowary TL), Cumpstey I*  (2011-03)  Eur. J. Org. Chem.  2011(7), 1367–1375  "Carbasugar Analogues of Galactofuranosides: Pseudodisaccharide Mimics of Fragments of Mycobacterial Arabino­galactan"
  130. Harrison JA, Kartha KP, Fournier EJ, (Lowary TL), Malet C, Nilsson UJ, Hindsgaul O, Schenkman S, Naismith JH, Field RA  (2011-03)  Organic & biomolecular chemistry  9(5), 1653-1660  "Probing the acceptor substrate binding site of Trypanosoma cruzi trans-sialidase with systematically modified substrates and glycoside libraries."
  131. Shi W, (Lowary TL)*  (2011-03)  Bioorganic & medicinal chemistry  19(5), 1779-1789  "Structure-activity relationships in glycosylated 2-phenyl-indoles, 2-phenyl-benzo[b]thiophenes and 2-phenyl-benzo[b]furans as DNA binding and potential antitumor agents."
  132. Taha HA, Roy PN*, (Lowary TL)*  (2011-02)  Journal of chemical theory and computation  7(2), 420-432  "Theoretical Investigations on the Conformation of the beta-d-Arabinofuranoside Ring."
  133. Shi W, Marcus SL, (Lowary TL)*  (2011-01)  Bioorganic & medicinal chemistry  19(1), 603-612  "Cytotoxicity and topoisomerase I/II inhibition of glycosylated 2-phenyl-indoles, 2-phenyl-benzo[b]thiophenes and 2-phenyl-benzo[b]furans."
  134. Liu C, Richards MR, (Lowary TL)*  (2011-01)  Organic & biomolecular chemistry  9(1), 165-176  "Synthesis and NMR spectroscopic analysis of acylated pentasaccharide fragments of mycobacterial arabinogalactan."
  135. Vembaiyan K, Pearcey JA, Bhasin M, (Lowary TL), Zou W*  (2011-01)  Bioorganic & medicinal chemistry  19(1), 58-66  "Synthesis of sugar-amino acid-nucleosides as potential glycosyltransferase inhibitors."
  136. Imamura A, (Lowary TL)*  (2011)  Trends in Glycoscience and Glycotechnology  23(131), 134–152  "Chemical Synthesis of Furanose Glycosides"
  137. Peltier P, Belanova M, Dianiskova P, Zhou R, Zheng RB, Pearcey JA, Joe M, Brennan PJ, Nugier-Chauvin C, Ferrieres V, (Lowary TL)*, Daniellou R*, Mikusova K*  (2010-12)  Chemistry & biology  17(12), 1356-1366  "Synthetic UDP-furanoses as potent inhibitors of mycobacterial galactan biogenesis."
  138. Meloncelli PJ, (Lowary TL)*  (2010-11)  Carbohydrate research  345(16), 2305-2322  "Synthesis of ABO histo-blood group type I and II antigens."
  139. Oppenheimer M, Poulin MB, (Lowary TL), Helm RF, Sobrado P*  (2010-10)  Archives of biochemistry and biophysics  502(1), 31-38  "Characterization of recombinant UDP-galactopyranose mutase from Aspergillus fumigatus."
  140. Imamura A, (Lowary TL)*  (2010-08)  Organic letters  12(16), 3686-3689  "Beta-selective arabinofuranosylation using a 2,3-O-xylylene-protected donor."
  141. Yang G, Li J, Liu Y, (Lowary TL), Xu Y*  (2010-08)  Organic & biomolecular chemistry  8(16), 3777-3783  "Determination of the absolute configurations of bicyclo[3.1.0]hexane derivatives via electronic circular dichroism, optical rotation dispersion and vibrational circular dichroism spectroscopy and density functional theory calculations."
  142. Yang G, Tran H, Fan E, Shi W, (Lowary TL), Xu Y*  (2010-08)  Chirality  22(8), 734-743  "Determination of the absolute configurations of synthetic daunorubicin analogues using vibrational circular dichroism spectroscopy and density functional theory."
  143. Liu C, Richards MR, (Lowary TL)*  (2010-08)  The Journal of organic chemistry  75(15), 4992-5007  "Probing the effect of acylation on arabinofuranose ring conformation in di- and trisaccharide fragments of mycobacterial arabinogalactan."
  144. Szczepina MG, Zheng RB, Completo GC, (Lowary TL)*, Pinto BM*  (2010-07)  Bioorganic & medicinal chemistry  18(14), 5123-5128  "STD-NMR studies of two acceptor substrates of GlfT2, a galactofuranosyltransferase from Mycobacterium tuberculosis: epitope mapping studies."
  145. Poulin MB, Nothaft H, Hug I, Feldman MF, Szymanski CM*, (Lowary TL)*  (2010-01)  The Journal of biological chemistry  285(1), 493-501  "Characterization of a bifunctional pyranose-furanose mutase from Campylobacter jejuni 11168."
  146. Taha HA, Castillo NC, Sears DN, Wasylishen RE, (Lowary TL)*, Roy PN*  (2010-01)  J. Chem. Theory Comput.  6(1), 212–222  "Conformational Analysis of Arabinofuranosides: Prediction of 3JH,H Using MD Simulations with DFT-Derived Spin−Spin Coupling Profiles"
  147. Tam PH, (Lowary TL)*  (2010-01)  Organic & biomolecular chemistry  8(1), 181-192  "Epimeric and amino disaccharide analogs as probes of an alpha-(1-->6)-mannosyltransferase involved in mycobacterial lipoarabinomannan biosynthesis."
  148. Shi W, Marcus SL, (Lowary TL)*  (2010-01)  Carbohydrate research  345(1), 10-22  "Synthesis and antibacterial activity of aminosugar-functionalized intercalating agents."
  149. Poulin MB, (Lowary TL)*  (2010)  Methods in enzymology  478, 389-411  "Methods to study the biosynthesis of bacterial furanosides."
  150. Tam PH, (Lowary TL)*  (2009-12)  Current opinion in chemical biology  13(5-6), 618-625  "Recent advances in mycobacterial cell wall glycan biosynthesis."
  151. Pan Y, (Lowary TL)*, Tykwinksi RR*  (2009-10)  Canadian Journal of Chemistry  87(11), 1565-1582  "Naturally Occurring and Synthetic Polyyne Glycosides"
  152. Hou D, (Lowary TL)*  (2009-10)  Carbohydrate research  344(15), 1911-1940  "Recent advances in the synthesis of 2-deoxy-glycosides."
  153. Hou D, Taha HA, (Lowary TL)*  (2009-09)  Journal of the American Chemical Society  131(36), 12937-12948  "2,3-Anhydrosugars in glycoside bond synthesis: mechanism of 2-deoxy-2-thioaryl glycoside formation."
  154. Murase T, Zheng RB, Joe M, Bai Y, Marcus SL, (Lowary TL)*, Ng KK*  (2009-09)  Journal of molecular biology  392(2), 381-392  "Structural insights into antibody recognition of mycobacterial polysaccharides."
  155. Shi W, Coleman RS, (Lowary TL)*  (2009-09)  Organic & biomolecular chemistry  7(18), 3709-3722  "Synthesis and DNA-binding affinity studies of glycosylated intercalators designed as functional mimics of the anthracycline antibiotics."
  156. Hou D, (Lowary TL)*  (2009-08)  Tetrahedron  65(31), 5916–5921  "2,3-Anhydrosugars in glycoside bond synthesis: application to furanosyl azides and C-glycosides"
  157. Richards MR, (Lowary TL)*  (2009-08)  Chembiochem : a European journal of chemical biology  10(12), 1920-1938  "Chemistry and biology of galactofuranose-containing polysaccharides."
  158. Szczepina MG, Zheng RB, Completo GC, (Lowary TL)*, Pinto BM*  (2009-08)  Chembiochem : a European journal of chemical biology  10(12), 2052-2059  "STD-NMR studies suggest that two acceptor substrates for GlfT2, a bifunctional galactofuranosyltransferase required for the biosynthesis of Mycobacterium tuberculosis arabinogalactan, compete for the same binding site."
  159. Meloncelli PJ, Martin AD, (Lowary TL)*  (2009-06)  Carbohydrate Research  344(9), 1110–1122  "Glycosyl iodides. History and Recent advances"
  160. Meloncelli PJ, (Lowary TL)*  (2009-06)  Australian Journal of Chemistry  62(6), 558-574  "Synthesis of ABO Histo-Blood Group Type V and VI Antigens"
  161. Carapito R, Imberty A, Jeltsch JM, Byrns SC, Tam PH, (Lowary TL), Varrot A*, Phalip V  (2009-05)  The Journal of biological chemistry  284(18), 12285-12296  "Molecular basis of arabinobio-hydrolase activity in phytopathogenic fungi: crystal structure and catalytic mechanism of Fusarium graminearum GH93 exo-alpha-L-arabinanase."
  162. Hou D, (Lowary TL)*  (2009-03)  The Journal of organic chemistry  74(6), 2278-2289  "2,3-Anhydrosugars in glycoside bond synthesis. Application to 2,6-dideoxypyranosides."
  163. Taha HA, Castillo N, Roy PN,* (Lowary TL)*  (2009-01)  J. Chem. Theory Comput.  5(2), 430–438  "Conformational Studies of Methyl β-d-Arabinofuranoside Using the AMBER/GLYCAM Approach"
  164. Birch HL, Alderwick LJ, Bhatt A, Rittmann D, Krumbach K, Singh A, Bai Y, (Lowary TL), Eggeling L, Besra GS*  (2008-09)  Molecular microbiology  69(5), 1191-1206  "Biosynthesis of mycobacterial arabinogalactan: identification of a novel alpha(1-->3) arabinofuranosyltransferase."
  165. Phillips RL, Kim IK, Carson BE, Tidbeck B, Bai Y, (Lowary TL), Bunz UHF*  (2008-09)  Macromolecules  41(20), 7316–7320  "Sugar-Substituted Poly(p-phenyleneethynylene)s: Sensitivity Enhancement toward Lectins and Bacteria"
  166. Rose NL, Zheng RB, Pearcey J, Zhou R, Completo GC, (Lowary TL)*  (2008-08)  Carbohydrate research  343(12), 2130-2139  "Development of a coupled spectrophotometric assay for GlfT2, a bifunctional mycobacterial galactofuranosyltransferase."
  167. Shi L, Zhou R, Liu Z, (Lowary TL), Seeberger PH, Stocker BL, Crick DC, Khoo KH, Chatterjee D*  (2008-08)  Journal of bacteriology  190(15), 5248-5255  "Transfer of the first arabinofuranose residue to galactan is essential for Mycobacterium smegmatis viability."
  168. Hou D, Skogman F, (Lowary TL)*  (2008-07)  Carbohydrate research  343(10-11), 1778-1789  "Synthesis of 8-azidooctyl glycoside derivatives of the O-chain repeating unit of Escherichia coli O9a lipopolysaccharide and a methylated analog."
  169. Completo GC, (Lowary TL)*  (2008-06)  The Journal of organic chemistry  73(12), 4513-4525  "Synthesis of galactofuranose-containing acceptor substrates for mycobacterial galactofuranosyltransferases."
  170. Alfaro JA, Zheng RB, Persson M, Letts JA, Polakowski R, Bai Y, Borisova SN, Seto NO, (Lowary TL), Palcic MM, Evans SV*  (2008-04)  The Journal of biological chemistry  283(15), 10097-10108  "ABO(H) blood group A and B glycosyltransferases recognize substrate via specific conformational changes."
  171. Appelmelk BJ*, den Dunnen J, Driessen NN, Ummels R, Pak M, Nigou J, Larrouy-Maumus G, Gurcha SS, Movahedzadeh F, Geurtsen J, Brown EJ, Eysink Smeets MM, Besra GS, Willemsen PT, (Lowary TL), van Kooyk Y, Maaskant JJ, Stoker NG, van der Ley P, Puzo G, Vandenbroucke-Grauls CM, Wieland CW, van der Poll T, Geijtenbeek TB, van der Sar AM, Bitter W  (2008-04)  Cellular microbiology  10(4), 930-944  "The mannose cap of mycobacterial lipoarabinomannan does not dominate the Mycobacterium-host interaction."
  172. Li J, (Lowary TL)*  (2008-03)  Organic letters  10(5), 881-884  "Synthesis of bicyclo[3.1.0]hexane derivatives as conformationally restricted analogues of beta-arabinofuranosyl and alpha-galactofuranosyl rings."
  173. Belanova M, Dianiskova P, Brennan PJ, Completo GC, Rose NL, (Lowary TL), Mikusova K  (2008-02)  Journal of bacteriology  190(3), 1141-1145  "Galactosyl transferases in mycobacterial cell wall synthesis."
  174. Seo M, Castillo N, Ganzynkowicz R, Daniels CR, Woods RJ, (Lowary TL)*, Roy PN*  (2008-01)  Journal of chemical theory and computation  4(1), 184-191  "Approach for the Simulation and Modeling of Flexible Rings: Application to the alpha-D-Arabinofuranoside Ring, a Key Constituent of Polysaccharides from Mycobacterium tuberculosis."
  175. Tam PH, Besra GS, (Lowary TL)*  (2008-01)  Chembiochem  9(2), 267-278  "Exploring the substrate specificity of a mycobacterial polyprenol monophosphomannose-dependent alpha-(1-->6)-mannosyltransferase."
  176. Liu C, Skogman F, Cai Y, (Lowary TL)*  (2007-12)  Carbohydrate research  342(18), 2818-2825  "Synthesis of the 'primer-adaptor' trisaccharide moiety of Escherichia coli O8, O9, and O9a lipopolysaccharide."
  177. Hou D, (Lowary TL)*  (2007-10)  Organic letters  9(22), 4487-4490  "Stereoselective synthesis of 2-deoxy-furanosides from 2,3-anhydro-furanosyl thioglycosides."
  178. Tam PH, (Lowary TL)*  (2007-09)  Carbohydrate research  342(12-13), 1741-1772  "Synthesis of deoxy and methoxy analogs of octyl α-d-mannopyranosyl-(1→6)-α-d-mannopyranoside as probes for mycobacterial lipoarabinomannan biosynthesis."
  179. Rademacher C, Shoemaker GK, Kim HS, Zheng RB, Taha H, Liu C, Nacario RC, Schriemer DC, Klassen JS, Peters T, (Lowary TL)  (2007-08)  Journal of the American Chemical Society  129(34), 10489-10502  "Ligand specificity of CS-35, a monoclonal antibody that recognizes mycobacterial lipoarabinomannan: a model system for oligofuranoside-protein recognition."
  180. Voehringer D, Stanley SA, Cox JS, Completo GC, (Lowary TL), Locksley RM*  (2007-08)  Experimental Parasitology  116(4), 458–466  "Nippostrongylus brasiliensis: Identification of intelectin-1 and -2 as Stat6-dependent genes expressed in lung and intestine during infection"
  181. Joe M, Bai Y, Nacario RC, (Lowary TL)*  (2007-08)  Journal of the American Chemical Society  129(32), 9885-9901  "Synthesis of the docosanasaccharide arabinan domain of mycobacterial arabinogalactan and a proposed octadecasaccharide biosynthetic precursor."
  182. Fan E, Shi W, (Lowary TL)*  (2007-04)  The Journal of organic chemistry  72(8), 2917-2928  "Synthesis of daunorubicin analogues containing truncated aromatic cores and unnatural monosaccharide residues."
  183. Sefzik T, Houseknecht JB, Clark TM, Prasad S, (Lowary TL), Gan Z, Grandinetti PJ*  (2007-02)  Chemical Physics Letters  434(4-6), 312–315  "Solid-state 17O NMR in carbohydrates"
  184. Bai Y, (Lowary TL)*  (2006-12)  The Journal of organic chemistry  71(26), 9658-9671  "2,3-Anhydrosugars in glycoside bond synthesis. Application to alpha-D-galactofuranosides."
  185. Bai Y, (Lowary TL)*  (2006-12)  The Journal of organic chemistry  71(26), 9672-9680  "Synthesis of a pentasaccharide fragment of varianose, a cell wall polysaccharide from Penicillium varians."
  186. Joe M, (Lowary TL)*  (2006-11)  Carbohydrate research  341(16), 2723-2730  "Synthesis of 2-deoxy-2-fluoro analogs of polyprenyl beta-D-arabinofuranosyl phosphates."
  187. Mendlik MT, Tao P, Hadad CM, Coleman RS*, (Lowary TL)*  (2006-10)  The Journal of organic chemistry  71(21), 8059-8070  "Synthesis of L-daunosamine and L-ristosamine glycosides via photoinduced aziridination. Conversion to thioglycosides for use in glycosylation reactions."
  188. Chang GX, (Lowary TL)*  (2006-07)  Tetrahedron Letters  47(27), 4561–4564  "An olefin cross metathesis approach to C-disaccharide analogs of the α-d-arabinofuranosyl-(1→5)-α-d-arabinofuranoside motif found in the mycobacterial cell wall"
  189. Bai Y, Lin SJ, Qi G, Palcic MM, (Lowary TL)  (2006-07)  Carbohydrate research  341(10), 1702-1707  "Synthesis of n-octyl 2,6-dideoxy-alpha-L-lyxo-hexopyranosyl-(1-->2)-3-amino-3-deoxy-beta-D-galactopyra noside, an analog of the H-disaccharide antigen."
  190. Rose NL, Completo GC, Lin SJ, McNeil M, Palcic MM*, (Lowary TL)*  (2006-05)  Journal of the American Chemical Society  128(20), 6721-6729  "Expression, purification, and characterization of a galactofuranosyltransferase involved in Mycobacterium tuberculosis arabinogalactan biosynthesis."
  191. Joe M, Sun D, Taha H, Completo GC, Croudace JE, Lammas DA, Besra GS, (Lowary TL)*  (2006-04)  Journal of the American Chemical Society  128(15), 5059-5072  "The 5-deoxy-5-methylthio-xylofuranose residue in mycobacterial lipoarabinomannan. absolute stereochemistry, linkage position, conformation, and immunomodulatory activity."
  192. Ridgway KM, Shi W, Lin SJ, Palcic MM, (Lowary TL)*  (2006)  Canadian Journal of Chemistry  84(4), 642-649  "Chemical and Chemoenzymatic Synthesis of a Trisaccharide Fragment of Tsukamurella paurometabola Lipoarabinomannan"
  193. Tong M, Jacobi CE, van de Rijke FM, Kuijper S, van de Werken S, (Lowary TL), Hokke CH, Appelmelk BJ, Nagelkerke NJ, Tanke HJ, van Gijlswijk RP, Veuskens J, Kolk AH, Raap AK  (2005-06)  Journal of immunological methods  301(1-2), 154-163  "A multiplexed and miniaturized serological tuberculosis assay identifies antigens that discriminate maximally between TB and non-TB sera."
  194. Subramaniam V, Gurcha SS, Besra GS, (Lowary TL)*  (2005-02)  Bioorganic & medicinal chemistry  13(4), 1083-1094  "Modified mannose disaccharides as substrates and inhibitors of a polyprenol monophosphomannose-dependent alpha-(1-->6)-mannosyltransferase involved in mycobacterial lipoarabinomannan biosynthesis."
  195. Cociorva OM, Gurcha SS, Besra GS, (Lowary TL)*  (2005-02)  Bioorganic & medicinal chemistry  13(4), 1369-1379  "Oligosaccharides as inhibitors of mycobacterial arabinosyltransferases. Di- and trisaccharides containing C-3 modified arabinofuranosyl residues."
  196. Subramaniam V, Gurcha SS, Besra GS, (Lowary TL)*  (2005-01)  Tetrahedron: Asymmetry  15(2), 553–567  "Synthetic disaccharide analogs as potential substrates and inhibitors of a mycobacterial polyprenol monophosphomannose-dependent α-(1→6)-mannosyltransferase"
  197. Luu T, Shi W, (Lowary TL)*, Tykwinski RR  (2005)  Synthesis  2005(18), 3167-3178  "A Divergent Synthesis of Triyne Natural Products and Glycosylated Analogues Using a Carbenoid Rearrangement"
  198. Completo GC, Ponto JA, (Lowary TL)*  (2005)  Journal of Carbohydrate Chemistry  24(4-6), 517–527  "Synthesis of Oligosaccharide Fragments of the Lipoarabinomannan from Rhodococcus ruber"
  199. Tilekar JN, (Lowary TL)*  (2004-12)  Carbohydrate Research  339(18), 2895–2899  "An Efficient Route to Thioglycosides with the 2,3-Anhydro-D-ribo Stereochemistry"
  200. Centrone CA, (Lowary TL)*  (2004-11)  Bioorganic & medicinal chemistry  12(21), 5495-5503  "Sulfone and phosphinic acid analogs of decaprenolphosphoarabinose as potential anti-tuberculosis agents."
  201. Cociorva OM, (Lowary TL)*  (2004-03)  Carbohydrate research  339(4), 853-865  "Synthesis of oligosaccharides as potential inhibitors of mycobacterial arabinosyltransferases. Di- and trisaccharides containing C-5 modified arabinofuranosyl residues."
  202. Cociorva OM, (Lowary TL)*  (2004-02)  Tetrahedron  60(7), 1481–1489  "2,3-Anhydrosugars in glycoside bond synthesis. Application to the preparation of C-2 functionalized α-d-arabinofuranosides"
  203. Koppel EA, Ludwig IS, Hernandez MS, (Lowary TL), Gadikota RR, Tuzikov AB, Vandenbroucke-Grauls CM, van Kooyk Y, Appelmelk BJ, Geijtenbeek TB  (2004)  Immunobiology  209(1-2), 117-127  "Identification of the mycobacterial carbohydrate structure that binds the C-type lectins DC-SIGN, L-SIGN and SIGNR1."
  204. (Lowary TL)*  (2003-12)  Current opinion in chemical biology  7(6), 749-756  "Synthesis and conformational analysis of arabinofuranosides, galactofuranosides and fructofuranosides."
  205. (Lowary TL)*  (2003-11)  Mini reviews in medicinal chemistry  3(7), 689-702  "Recent progress towards the identification of inhibitors of mycobacterial cell wall polysaccharide biosynthesis."
  206. Callam CS, Gadikota RR, Krein DM, (Lowary TL)*  (2003-10)  Journal of the American Chemical Society  125(43), 13112-13119  "2,3-anhydrosugars in glycoside bond synthesis. NMR and computational investigations into the mechanism of glycosylations with 2,3-anhydrofuranosyl glycosyl sulfoxides."
  207. Centrone CA, (Lowary TL)*  (2003-10)  The Journal of organic chemistry  68(21), 8115-8119  "An efficient route for the synthesis of glycosyl phosphinic acids."
  208. Callam CS, Gadikota RR, (Lowary TL)*  (2003-07)  Synlett  9(S1), 1271-1274  "An Efficient Route to Pyrimidine Nucleosides with the 2,3-Anhydro-β-D-lyxofuranosyl Stereochemistry"
  209. Houseknecht JB, (Lowary TL)*, Hadad CM*  (2003-07)  J. Phys. Chem. A  107(30), 5763–5777  "Gas- and Solution-Phase Energetics of the Methyl α- and β-d-Aldopentofuranosides"
  210. Han JS, (Lowary TL)*  (2003-05)  The Journal of organic chemistry  68(10), 4116-4119  "Total synthesis of buergerinin F and buergerinin G."
  211. Gadikota RR, Callam CS, Wagner T, Del Fraino B, (Lowary TL)*  (2003-04)  Journal of the American Chemical Society  125(14), 4155-4165  "2,3-Anhydro sugars in glycoside bond synthesis. Highly stereoselective syntheses of oligosaccharides containing alpha- and beta-arabinofuranosyl linkages."
  212. Gadikota RR, Keller AI, Callam CS, (Lowary TL)*  (2003-03)  Tetrahedron: Asymmetry  14(6), 737–742  "Efficient Syntheses of trans-(+)-Laurediol from Carbohydrate Precursors"
  213. Han J, Gadikota RR, McCarren PR, (Lowary TL)*  (2003-03)  Carbohydrate research  338(7), 581-588  "Synthesis of octyl arabinofuranosides as substrates for mycobacterial arabinosyltransferases."
  214. Houseknecht JB, (Lowary TL)*, Hadad CM*  (2003)  J. Phys. Chem. A  107(3), 372-378  "Improved Karplus Equations for 3JC1,H4 in Aldopentofuranosides. Application to the Conformational Preferences of the Methyl Aldopentofuranosides"
  215. Darwish O, Callam CS, Hadad CM, (Lowary TL)*  (2003)  Journal of Carbohydrate Chemistry  22(9), 963–981  "Regioselectivity in Alkylation Reactions of 1,2-O-Stannylene Acetals of D-Arabinofuranose"
  216. Gadikota RR, Callam CS, Appelmelk BJ, (Lowary TL)*  (2003)  Journal of Carbohydrate Chemistry  22(6), 459–480  "Synthesis of Oligosaccharide Fragments of Mannosylated Lipoarabinomannan Appropriately Functionalized for Neoglycoconjugate Preparation"
  217. Centrone CA, (Lowary TL)*  (2002-12)  The Journal of organic chemistry  67(25), 8862-8870  "Synthesis and antituberculosis activity of C-phosphonate analogues of decaprenolphosphoarabinose, a key intermediate in the biosynthesis of mycobacterial arabinogalactan and lipoarabinomannan."
  218. Kaur D, (Lowary TL), Vissa VD, Crick DC, Brennan PJ  (2002-10)  Microbiology  148(Pt 10), 3049-3057  "Characterization of the epitope of anti-lipoarabinomannan antibodies as the terminal hexaarabinofuranosyl motif of mycobacterial arabinans."
  219. Krein DM, (Lowary TL)*  (2002-07)  The Journal of organic chemistry  67(14), 4965-4967  "A convenient synthesis of 2-(alkylamino)pyridines."
  220. Houseknecht JB, Altona C, Hadad CM, (Lowary TL)*  (2002-07)  The Journal of organic chemistry  67(14), 4647-4651  "Conformational analysis of furanose rings with PSEUROT: parametrization for rings possessing the arabino, lyxo, ribo, and xylo stereochemistry and application to arabinofuranosides."
  221. Houseknecht JB, (Lowary TL)*  (2002-06)  The Journal of organic chemistry  67(12), 4150-4164  "Oligofuranosides containing conformationally restricted residues: synthesis and conformational analysis."
  222. Yin H, D'Souza FW, (Lowary TL)*  (2002-02)  The Journal of organic chemistry  67(3), 892-903  "Arabinofuranosides from mycobacteria: synthesis of a highly branched hexasaccharide and related fragments containing beta-arabinofuranosyl residues."
  223. (Lowary TL)*  (2002)  Journal of Carbohydrate Chemistry  21(7-9), 691–722  "D-Arabinofuranosides from Mycobacteria: Synthesis and Conformation"
  224. (Lowary TL), Eichler E, Bundle DR  (2002)  Canadian Journal of Chemistry  80(8), 1112-1130  "Oligosaccharide Recognition by Antibodies: Synthesis and Evaluation of Talose Oligosaccharide Analogues"
  225. Basak P, (Lowary TL)*  (2002)  Canadian Journal of Chemistry  80(8), 943–948  "Synthesis of Conjugates of L-Fucose and ortho-Carborane as Potential Agents for Boron Neutron Capture Therapy"
  226. Houseknecht JB, (Lowary TL)*  (2001-12)  Current opinion in chemical biology  5(6), 677-682  "Chemistry and biology of arabinofuranosyl- and galactofuranosyl-containing polysaccharides."
  227. Callam CS, (Lowary TL)*  (2001-12)  The Journal of organic chemistry  66(26), 8961-8972  "Synthesis and conformational investigation of methyl 4a-carba-D-arabinofuranosides."
  228. Gadikota RR, Callam CS, (Lowary TL)*  (2001-12)  The Journal of organic chemistry  66(26), 9046-9051  "Total synthesis of (2S,3S,5S,10S)-6,9-epoxynonadec-18-ene-7,10-diol and formal total synthesis of (+)-trans-kumausyne from D-arabinose."
  229. Callam CS, Singer SJ, (Lowary TL)*, Hadad CM*  (2001-11)  Journal of the American Chemical Society  123(47), 11743-11754  "Computational analysis of the potential energy surfaces of glycerol in the gas and aqueous phases: effects of level of theory, basis set, and solvation on strongly intramolecularly hydrogen-bonded systems."
  230. Houseknecht JB, McCarren PR, (Lowary TL)*, Hadad CM*  (2001-09)  Journal of the American Chemical Society  123(36), 8811-8824  "Conformational studies of methyl 3-O-methyl-alpha-D-arabinofuranoside: an approach for studying the conformation of furanose rings."
  231. Yin HF, (Lowary TL)*  (2001-08)  Tetrahedron Letters  42(34), 5829–5832  "Synthesis of Arabinofuranosides via Low-Temperature Activation of Thioglycosides"
  232. Callam CS, (Lowary TL)*  (2001-07)  J. Chem. Educ.  78, 947–948  "Suzuki Cross-Coupling Reactions: Synthesis of Unsymmetrical Biaryls in the Organic Laboratory"
  233. Callam CS, Gadikota RR, (Lowary TL)*  (2001-06)  The Journal of organic chemistry  66(13), 4549-4558  "Sensitivity of (1)J[C(1)-H(1)] magnitudes to anomeric stereochemistry in 2,3-anhydro-O-furanosides."
  234. McCarren PR, Gordon MT, (Lowary TL)*, Hadad CM*  (2001-05)  J. Phys. Chem. A.  105, 5911–5922  "Computational Studies of the Arabinofuranose Ring:  Conformational Preferences of Fully Relaxed Methyl α-d-arabinofuranoside"
  235. McGurk P, Chang GX, (Lowary TL), McNeil M, Field RA  (2001-03)  Tetrahedron Letters  42(11), 2231–2234  "Stereospecific Synthesis of 5-Phospho-α-D-arabinosyl-C-phosphonophosphate (pACpp): A Stable Analogue of the Putative Mycobacterial Cell Wall Biosynthetic Intermediate 5-Phospho-D-arabinosyl Pyrophosphate"
  236. Gadikota RR, Callam CS, (Lowary TL)*  (2001-02)  Organic letters  3(4), 607-610  "Stereocontrolled synthesis of 2,3-anhydro-beta-d-lyxofuranosyl glycosides."
  237. Callam CS, Gadikota RR, (Lowary TL)*  (2001-01)  Carbohydrate research  330(2), 267-270  "An efficient synthesis of methyl 2,3-anhydro-alpha-D-ribofuranoside."
  238. Callam CS, (Lowary TL)*  (2001-01)  J. Chem. Educ.  78, 73–74  "Synthesis of Methyl 2,3,5-tri-O-benzoyl-α-D-Arabinofuranoside in the Organic Laboratory"
  239. Laferte S, Chan NW, Sujino K, (Lowary TL), Palcic MM  (2000-08)  European journal of biochemistry  267(15), 4840-4849  "Intracellular inhibition of blood group A glycosyltransferase."
  240. Gordon MT, (Lowary TL)*, Hadad CM*  (2000-08)  The Journal of organic chemistry  65(16), 4954-4963  "Probing furanose ring conformation by gas-phase computational methods: energy profile and structural parameters in methyl beta-D-arabinofuranoside as a function of ring conformation"
  241. Chang GX, (Lowary TL)*  (2000-06)  Organic letters  2(11), 1505-1508  "A glycosylation protocol based on activation of glycosyl 2-pyridyl sulfones with samarium triflate."
  242. D'Souza FW, (Lowary TL)*  (2000-05)  Organic letters  2(10), 1493-1495  "The first total synthesis of a highly branched arabinofuranosyl hexasaccharide found at the nonreducing termini of mycobacterial arabinogalactan and lipoarabinomannan."
  243. D’Souza FW, Ayers JD, McCarren PR, (Lowary TL)*  (2000-02)  J. Am. Chem. Soc.  122, 1251–1260  "Arabinofuranosyl Oligosaccharides from Mycobacteria: Synthesis and Effect of Glycosylation on Ring Conformation and Hydroxymethyl Group Rotamer Populations"
  244. Davis TM, (Lowary TL)*  (2000-02)  Carbohydrate research  324(3), 210-217  "Unexpected formation of glycals upon attempted C-alkylation of protected glycosylacetylenes."
  245. Callam CS, (Lowary TL)*  (2000-01)  Organic letters  2(2), 167-169  "Total synthesis of both methyl 4a-carba-D-arabinofuranosides."
  246. Gordon MT, (Lowary TL)*, Hadad CM*  (1999-10)  J. Am. Chem. Soc.  121, 9682–9692  "A Computational Study of Methyl α-D-Arabinofuranoside: Effect of Ring Conformation on Structural Parameters and Energy Profile"
  247. Subramaniam V, (Lowary TL)*  (1999-05)  Tetrahedron  55(19), 5965–5976  "Synthesis of Oligosaccharide Fragments of Mannosylated Lipoarabinomannan from Mycobacterium tuberculosis"
  248. (Lowary TL), Meldal M Helmboldt A, Vasella A, Bock K  (1998-12)  J. Org. Chem.  63, 9657–9668  "Novel Rigid Type of C-linked Glycosylacetylene Phenylalanine Building Blocks for Combinatorial Syntheses of C-Linked Glycopeptides"
  249. St Hilaire PM, (Lowary TL), Meldal M, Bock K  (1998-12)  J. Am. Chem. Soc.  120, 13312–13320  "Oligosaccharide Mimetics Obtained by Novel, Rapid Screening of Carboxylic Acid Encoded Glycopeptide Libraries"
  250. D’Souza FW, Cheshev PE, Ayers JD, (Lowary TL)*  (1998-11)  J. Org. Chem.  63, 9037–9044  "Conversion of Pyranose Glycals to Furanose Derivatives: A New Route to Oligofuranosides"
  251. Bausch C, Peekhaus N, Utz C, Blais T, Murray E, (Lowary T), Conway T  (1998-07)  Journal of bacteriology  180(14), 3704-3710  "Sequence analysis of the GntII (subsidiary) system for gluconate metabolism reveals a novel pathway for L-idonic acid catabolism in Escherichia coli."
  252. D’Souza FW, (Lowary TL)*  (1998-04)  J. Org. Chem.  63, 3166–3167  "A New Route to Carbohydrates Enriched with Oxygen Isotopes"
  253. Ayers JD, (Lowary TL)*, Morehouse CB, Besra GS  (1998-03)  Bioorganic & medicinal chemistry letters  8(5), 437-442  "Synthetic arabinofuranosyl oligosaccharides as mycobacterial arabinosyltransferase substrates."
  254. Greis KD, Hayes BK, Comer FI, Kirk M, Barnes S, (Lowary TL), Hart GW  (1996-02)  Analytical biochemistry  234(1), 38-49  "Selective detection and site-analysis of O-GlcNAc-modified glycopeptides by beta-elimination and tandem electrospray mass spectrometry."
  255. (Lowary TL), Eichler E, Bundle DR  (1995-11)  J. Org. Chem.  60, 7316–7327  "Synthesis of a Pentasaccharide Epitope for the Investigation of Carbohydrate-Protein Interactions."
  256. Deng SJ, MacKenzie CR, Hirama T, Brousseau R, (Lowary TL), Young NM, Bundle DR, Narang SA  (1995-05)  Proceedings of the National Academy of Sciences of the United States of America  92(11), 4992-4996  "Basis for selection of improved carbohydrate-binding single-chain antibodies from synthetic gene libraries."
  257. Peters S, (Lowary TL), Hindsgaul O, Meldal M, Bock K  (1995)  J. Chem. Soc., Perkin Trans. 1  1995, 3017-3022  "Solid-phase synthesis of a fucosylated glycopeptide of human factor IX with a fucose-α-(1→O)-serine linkage"
  258. (Lowary TL), Bundle DR  (1994-12)  Tetrahedron: Asymmetry  5(12), 2397–2404  "Nucleophile Induced Rearrangements of Thioglycosides: Formation of 6-Thio Glycosides and 1,6 Thioanhydrosugars"
  259. (Lowary TL), Swiedler SJ, Hindsgaul O  (1994-04)  Carbohydrate Research  256(2), 257-273  "Recognition of synthetic analogues of the acceptor, β-D-Galp-OR, by the blood-group H gene-specified glycosyltransferase."
  260. (Lowary TL), Hindsgaul O  (1994-01)  Carbohydrate Research  251, 33-67  "Recognition of synthetic O-methyl, epimeric, and amino analogues of the acceptor α-L-Fucp-(1 → 2)-β-D-Galp-OR by the blood-group A and B gene-specified glycosyltransferases."
  261. (Lowary TL) Hindsgaul O  (1993-10)  Carbohydrate Research  249(1), 163–195  "Recognition of Synthetic Deoxy and Deoxyfluoro Analogs of the Acceptor α-L-Fucp-(1 → 2)-β-D-Galp-OR by the Blood-Group A and B Gene-Specified Glycosyltransferases"
  262. (Lowary TL), Richards GN  (1991-09)  Carbohydrate Research  218, 157–166  "Cycloheptaamylose as a Model for Starch in the Pyrolysis of Polysaccharides"
  263. (Lowary TL), Richards GN  (1990-04)  Carbohydrate Research  198(1), 79–89  "Mechanisms of Pyrolysis of Polysaccharides: Cellobiitol as a Model for Cellulose"
  264. (Lowary TL), Richards GN  (1989)  Journal of Wood Chemistry and Technology  9(3), 333-339  "Analysis of a Hydroxystilbene Glucoside in Several Softwood Barks"
  265. (Lowary TL), Richards GN  (1988)  Int. Sugar J.  90, 164-167  "Effects of Impurities on the Hydrolysis of Sucrose in Concentrated Aqueous Solution"
  266. (Lowary TL), Richards GN  (1988)  Journal of Wood Chemistry and Technology  8(3), 393-412  "Vacuum Pyrolysis of Bark from Pinus ponderosa"