廖俊智教授的研究領域為代謝及合成生物學, 特別在以微生物合成燃料的領域,及基礎代謝路徑的改造。此外,他更發展出網路構成要素分析法(Network Component Analysis) 及Ensemble Modeling,用以分析複雜的轉錄組調控,及設計人工基因轉錄調控迴路。
Augmenting the Calvin-Benson-Bassham cycle by a synthetic malyl-CoA-glycerate carbon fixation pathway.
Yu H, Li X, Duchoud F, Chuang DS, Liao JC
Nature communications (2018)
Construction and evolution of an Escherichia coli strain relying on nonoxidative glycolysis for sugar catabolism.
Lin PP, Jaeger AJ, Wu TY, Xu SC, Lee AS, Gao F, Chen PW, Liao JC
Proc Natl Acad Sci USA (2018)
Metabolic repair through emergence of new pathways in Escherichia coli.
Pontrelli S, Fricke RCB, Teoh ST, Lavina WA, Putri SP, Fitz-Gibbon S, Chung M, Pellegrini M, Fukusaki E, Liao JC
Nature chemical biology (2018)
Synthetic non-oxidative glycolysis enables complete carbon conservation.
Bogorad IW, Lin TS, Liao JC
Nature (2013)
Integrated electromicrobial conversion of CO2 to higher alcohols.
Li, H.; P.H. Opgenorth; D.G. Wernick; S. Rogers; T.-Y.Wu; W. Higashide; P. Malati; Y. Huo, K.-M. Cho, and J.C. Liao
Science (2012)
Direct photosynthetic recycling of carbon dioxide to isobutyraldehyde.
Atsumi, S.; Higashide, W.; and J.C. Liao
Nature Biotechnol (2009)
Resistance to Diet-Induced Obesity in Mice with Synthetic Glyoxylate Shunt.
Dean, J.T.; Tran, L.; Beaven, S.; Tontonoz, P; Reue, K.; Dipple, K.D.; and J.C. Liao
Cell Metabolism (2009)
Expanding Metabolism for Biosynthesis of Nonnatural Alcohols.
Zhang, K., Sawaya, M.R., Eisenberg, D.S. and J.C. Liao
Proc. Natl. Acad. Sci. USA (2008)
Non-Fermentative Pathways for Synthesis of Branched-Chain Higher Alcohols as Biofuels.
Atsumi, S.; T. Hanai and J.C. Liao
Nature (2008)
A synthetic gene-metabolic oscillator.
Fung, E.; Wong, W.W.; Suen, J.K.; Bulter, T.; Lee, S.G.; and J.C. Liao
Nature (2005)