退休研究人員
洪金俊 研究副技師

研究領域與專長

  1. Providing training and technical expertise to IBC investigators interested in using microscopy, flow cytometer and scientific imaging in their research
  2. Modalities and techniques including laser scanning confocal microscopy, wide-field fluorescence microscopy, live cell imaging
  3. In depth collaboration on select projects involving advanced microscopy techniques and methodologies
  4. Maintenance of the instrumentation and associated infrastructure
  5. Assistance with educational microscopy courses conducted at IBC

學經歷

  • 2001   博士, 生物化學, 國立臺灣大學
  • 2014 – 2022   研究副技師, 中研院生化所
  • 2009 – 2014   研究助技師, 中研院生化所
  • 1992 – 2008   研究助理, 中研院生化所

主要著作

Intermolecular binding between TIFA-FHA and TIFA-pT mediates tumor necrosis factor alpha stimulation and NF-kappaB activation. 
Huang CC, Weng JH, Wei TY, Wu PY, Hsu PH, Chen YH, Wang SC, Qin D, Hung CC, Chen ST, Wang AH, Shyy JY, Tsai MD 
Molecular and cellular biology (2012)

Phosphorylation of the zebrafish M6Ab at serine 263 contributes to filopodium formation in PC12 cells and neurite outgrowth in zebrafish embryos. 
Huang KY, Chen GD, Cheng CH, Liao KY, Hung CC, Chang GD, Hwang PP, Lin SY, Tsai MC, Khoo KH, Lee MT, Huang CJ 
PloS one (2011)

Synthesis and structure-activity relationships of novel furazan-3,4-diamide analogs as potent anti-cancer agents. 
Li WS, More SV, Wang CH, Jen YC, Yao CF, Wang TF, Hung CC, Jao SC 
Bioorganic & medicinal chemistry letters (2010)

Up-regulation of fibronectin and tissue transglutaminase promotes cell invasion involving increased association with integrin and MMP expression in A431 cells. 
Chen SH, Lin CY, Lee LT, Chang GD, Lee PP, Hung CC, Kao WT, Tsai PH, Schally AV, Hwang JJ, Lee MT 
Anticancer research (2010)

Recapitulation of zebrafish sncga expression pattern and labeling the habenular complex in transgenic zebrafish using green fluorescent protein reporter gene. 
Chen YC, Cheng CH, Chen GD, Hung CC, Yang CH, Hwang SP, Kawakami K, Wu BK, Huang CJ 
Developmental dynamics (2009)

Investigation of MMP-2 and -9 in a highly invasive A431 tumor cell sub-line selected from a Boyden chamber assay. 
Kao WT, Lin CY, Lee LT, Lee PP, Hung CC, Lin YS, Chen SH, Ke FC, Hwang JJ, Lee MT 
Anticancer research (2008)

The zebrafish erythropoietin: functional identification and biochemical characterization. 
Chu CY, Cheng CH, Chen GD, Chen YC, Hung CC, Huang KY, Huang CJ 
FEBS letters (2007)

Requirement of nuclear localization and transcriptional activity of p53 for its targeting to the yolk syncytial layer (YSL) nuclei in zebrafish embryo and its use for apoptosis assay. 
Chen GD, Chou CM, Hwang SP, Wang FF, Chen YC, Hung CC, Chen JY, Huang CJ 
Biochemical and biophysical research communications (2006)

Crystal structure of a platelet-agglutinating factor isolated from the venom of Taiwan habu (Trimeresurus mucrosquamatus). 
Huang KF, Ko TP, Hung CC, Chu J, Wang AH, Chiou SH 
The Biochemical journal (2004)

3-phosphoinositide-dependent protein kinase-1/Akt signaling represents a major cyclooxygenase-2-independent target for celecoxib in prostate cancer cells. 
Kulp SK, Yang YT, Hung CC, Chen KF, Lai JP, Tseng PH, Fowble JW, Ward PJ, Chen CS 
Cancer research (2004)

著作列表