The study on relationship of structure and function of biomolecules is the main theme of our research. The basic techniques used in our studies include NMR, GC-Mass and MS, BIAcore, CD, organic synthesis, cloning, site-directed mutagenesis and other physical methods and chromatographies. At present, our works focus on several topics described as follows:
- Carbohydrate Chemistry and Glycobiology
- Drug Discovery and Development from the Secondary metabolites of microorganisms
- Studies on the structure-functional relationship of proteins and peptides by NMR and X-ray diffraction
- Proteomic studies
Wu WL, Liao JH, Lin GH, Lin MH, Chang YC, Liang SY, Yang FL, Khoo KH, Wu SH
Molecular & Cellular Proteomics (2013)
Lin MH, Yang YL, Chen YP, Hua KF, Lu CP, Sheu F, Lin GH, Tsay SS, Liang SM, Wu SH
Journal of biological chemistry (2011)
Liao JH, Chen CS, Hu CC, Chen WT, Wang SP, Lin IL, Huang YH, Tsai MH, Wu TH, Huang FY, Wu SH
Inorganic chemistry (2011)
Yang FL, Yang YL, Liao PC, Chou JC, Tsai KC, Yang AS, Sheu F, Lin TL, Hsieh PF, Wang JT, Hua KF, Wu SH
Journal of biological chemistry (2011)
Liaw CC, Liao WY, Chen CS, Jao SC, Wu YC, Shen CN, Wu SH
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2011)
Fang Z, Liao PC, Yang YL, Yang FL, Chen YL, Lam Y, Hua KF, Wu SH
Journal of medicinal chemistry (2010)
Y-L. Yang, W-Y. Liao, W-Y. Liu, C-C. Liaw, C-N. Shen, Z-Y. Huang, and S-H. Wu
CHEMISTRY-A EUROPEAN JOURNAL (2009)
Lin MH, Hsu TL, Lin SY, Pan YJ, Jan JT, Wang JT, Khoo KH, Wu SH.
Mol Cell Proteomics (2009)
Chen SH, Suzuki CK, Wu SH
Nucleic acids research (2008)
Y. L. Yang, C. P. Lu, M. Y. Chen, K. Y. Chen, Y. C. Wu and S. H. Wu
CHEMISTRY-A EUROPEAN JOURNAL (2007)