Latest Publications

2020 11 19 Chi P Epub
Human CST complex protects stalled replication forks by directly blocking MRE11 degradation of nascent-strand DNA

Dr. Chi P [...]

15
Jan
20201231 Lowary TL Epub
Use of Synthetic Glycolipids to Probe the Number and Position of Arabinan Chains on Mycobacterial Arabinogalactan

Dr. Lowary TL [...]

15
Jan
20201221 Wang AH Epub
Crystal structure of the N-terminal domain of TagH reveals a potential drug targeting site

Dr. Wang AH [...]

15
Jan
20210114 Tsai MD paper photo 1
Identification of fidelity-governing factors in human recombinases DMC1 and RAD51 from cryo-EM structures

Dr. Tsai MD & Dr. Chi P & Dr. Ho MC & Dr. Wu WJ [...]

14
Jan
20210113 Ho MC Epub
Single nucleotide variants lead to dysregulation of the human mitochondrial NAD(P)+-dependent malic enzyme

Dr. Ho MC [...]

13
Jan
20210112 Lin S Epub
A robust platform for expansion and genome editing of primary human natural killer cells

Dr. Lin S [...]

12
Jan
20201106 Lin S Epub
Humanized COVID-19 decoy antibody effectively blocks viral entry and prevents SARS-CoV-2 infection

Dr. Lin S [...]

11
Jan
20210105 Angata T paper photo
Siglec-E retards atherosclerosis by inhibiting CD36-mediated foam cell formation

Dr. Angata T [...]

05
Jan
20210102 Wu SH paper photo
New Hydroquinone Monoterpenoid and Cembranoid-Related Metabolites from the Soft Coral Sarcophyton tenuispiculatum

Dr. Wu SH [...]

02
Jan
20201127 Wang AH Epub
Structure, catalysis, and inhibition mechanism of prenyltransferase

Dr. Wang AH [...]

02
Jan
20201111 Khoo KH Epub
Sialylation of CD55 by ST3GAL1 facilitates immune evasion in cancer

Dr. Khoo KH [...]

02
Jan
20201119 Angata T Epub 1
A Guillain-Barré syndrome-associated SIGLEC10 rare variant impairs its recognition of gangliosides

Dr. Angata T [...]

01
Jan
20201215 Lin CH Epub
Threshold of Thioglycoside Reactivity Difference Is Critical for Efficient Synthesis of Type I Oligosaccharides by Chemoselective Glycosylation

Dr. Lin CH & Dr. Tu Z [...]

01
Jan
20201016 Lin CH Epub
Potent and orally active purine-based fetal hemoglobin inducers for treating β-thalassemia and sickle cell disease

Dr. Lin CH [...]

01
Jan
20201229 Liang PH Epub
Uncovering Flexible Active Site Conformations of SARS-CoV-2 3CL Proteases through Protease Pharmacophore Clusters and COVID-19 Drug Repurposing

Dr. Liang PH [...]

29
Dec
20201228 Wang AH Epub
Vibrio cholerae biofilm scaffolding protein RbmA shows an intrinsic, phosphate‐dependent autoproteolysis activity

Dr. Wang AH & Dr. Maestre-Reyna M & Dr. Tsai MD & Dr. Wu WJ & Dr. Bessho Y [...]

28
Dec
20200620 Wu SH Epub photo
Multimeric TAT Peptides Are Effective in Vitro Inhibitors of Staphylococcus Saprophyticus

Dr. Wu SH [...]

27
Dec
20201222 Wang AH Epub
Structure-based Development of Human Interleukin-1β-Specific Antibody That Simultaneously Inhibits Binding to Both IL-1RI and IL-1RAcP

Dr. Wang AH [...]

22
Dec
20201221 Liang PH cancers paper
Chaperonin-Containing TCP-1 Promotes Cancer Chemoresistance and Metastasis through the AKT-GSK3β-β-Catenin and XIAP-Survivin Pathways

Dr. Liang PH [...]

21
Dec
20201216 Shih YL paper photo
Peptidoglycan Endopeptidase Spr of Uropathogenic Escherichia coli Contributes to Kidney Infections and Competitive Fitness During Bladder Colonization

Dr. Shih YL [...]

16
Dec
20200928 Wu SH Epub 1
Phagocytosis enhancement, endotoxin tolerance, and signal mechanisms of immunologically active glucuronoxylomannan from Auricularia auricula-judae

Dr. Wu SH [...]

15
Dec
20200825 Lin CH Epub
Design, synthesis and molecular docking study of α-triazolylsialosides as non-hydrolyzable and potent CD22 ligands

Dr. Lin CH [...]

15
Dec
20201214 Liao JC
Role of cyanobacterial phosphoketolase in energy regulation and glucose secretion under dark anaerobic and osmotic stress conditions

Dr. Liao JC [...]

14
Dec
2020 12 10 Yao CK
A positive feedback loop between Flower and PI(4,5)P 2 at periactive zones controls bulk endocytosis in Drosophila

Dr. Yao CK [...]

10
Dec
20201201 Liao JC
Analysis of genomic distributions of SARS-CoV-2 reveals a dominant strain type with strong allelic associations

Dr. Liao JC [...]

01
Dec
20201124 Wu SH paper photo
Effect of membrane fusion protein AdeT1 on the antimicrobial resistance of Escherichia coli

Dr. Wu SH [...]

24
Nov
20201118 Wu SH Epub 2
Bacteriophage Tail-Spike Proteins Enable Detection of Pseudaminic-Acid-Coated Pathogenic Bacteria and Guide the Development of Antiglycan Antibodies with Cross-Species Antibacterial Activity

Dr. Wu SH [...]

18
Nov
20201102 Lowary TL Epub
Chlorovirus PBCV-1 protein A064R has three of the transferase activities necessary to synthesize its capsid protein N-linked glycans

Dr. Lowary TL [...]

17
Nov
20201113 Huang CJ Epub
Zebrafish Cdx1b modulates epithalamic asymmetry by regulating ndr2 and lft1 expression

Dr. Huang CJ [...]

13
Nov
20201109 Chen RH paper photo
Branched Ubiquitination: Detection Methods, Biological Functions and Chemical Synthesis

Dr. Wang YS & Dr. Wu KP & Dr. Chen RH [...]

09
Nov
20201102 Lowary TL paper photo
Diagnostic accuracy of 3 urine lipoarabinomannan tuberculosis assays in HIV-negative outpatients

Dr. Lowary TL [...]

02
Nov
20200729 Huang KF Epub photo
Cloning, expression, identification and characterization of borneol dehydrogenase isozymes in Pseudomonas sp. TCU-HL1

Dr. Huang KF [...]

01
Nov
20201028 PTPN9 Chen GC Epub
PTPN9-mediated dephosphorylation of VTI1B promotes ATG16L1 precursor fusion and autophagosome formation

Dr. Chen GC & Dr. Hung CC & Dr. Lin SY [...]

28
Oct
20201027 Yao CK paper photo
Dynamin-2 Regulates Postsynaptic Cytoskeleton Organization and Neuromuscular Junction Development

Dr. Yao CK [...]

27
Oct
20201019 Yang WY paper photo
Hsc70/Stub1 promotes the removal of individual oxidatively stressed peroxisomes

Dr. Yang WY & Dr. Lin S [...]

19
Oct
20200526 Tsai MD paper photo
Nonhydrolyzable Heptose Bis- and Monophosphate Analogues Modulate Pro-inflammatory TIFA-NF-κB Signaling

Dr. Tsai MD [...]

15
Oct
20201002 Wang YS Epub photo
Revealing USP7 Deubiquitinase Substrate Specificity by Unbiased Synthesis of Ubiquitin Tagged SUMO2

Dr. Wang YS & Dr. Lin SY [...]

13
Oct
20201008 Chen RP paper photo
Self-Replication of Prion Protein Fragment 89-230 Amyloid Fibrils Accelerated by Prion Protein Fragment 107-143 Aggregates

Dr. Chen RP [...]

08
Oct
20200816 Ho MR epub photo
Multiresolution Imaging Using Bioluminescence Resonance Energy Transfer Identifies Distinct Biodistribution Profiles of Extracellular Vesicles and Exomeres with Redirected Tropism

Dr. Ho MR [...]

07
Oct
20201002 Wu SH paper photo
Phosphoproteomics and Bioinformatics Analyses Reveal Key Roles of GSK-3 and AKAP4 in Mouse Sperm Capacitation

Dr. Wu SH [...]

02
Oct
20201002 Lowary TL paper photo
Synthesis of a Highly Branched Nonasaccharide Chlorella Virus N-Glycan Using a “Counterclockwise” Assembly Approach

Dr. Lowary TL [...]

02
Oct
20201001 Meng TC paper photo 1
Eating right for a healthier heart: Food choice contributes to cardiometabolic benefits and reduction of carotid intima-media thickness

Dr. Meng TC [...]

01
Oct
20200930 Chang CJ paper photo
TRIM28 Regulates Dlk1 Expression in Adipogenesis

Dr. Chang CJ & Dr. Lin SW [...]

30
Sep
20200928 Wang AHJ paper photo
Preparation and characterization of antibody-drug conjugates acting on HER2-positive cancer cells

Dr. Wang AH [...]

28
Sep
Molecules 2020 Sep Yane Shih Wang R1
Expanding the Scope of Orthogonal Translation with Pyrrolysyl-tRNA Synthetases Dedicated to Aromatic Amino Acids

Dr. Wang YS [...]

25
Sep
20200814 Lin S Epub
A multiplexed bioluminescent reporter for sensitive and non-invasive tracking of DNA double strand break repair dynamics in vitro and in vivo

Dr. Lin S [...]

25
Sep
20200921 Lin HC paper photo
Biosynthesis of the fungal glyceraldehyde-3-phosphate dehydrogenase inhibitor heptelidic acid and mechanism of self-resistance

Dr. Lin HC [...]

21
Sep
20200731 Chi P Epub
Microcephaly family protein MCPH1 stabilizes RAD51 filaments

Dr. Chi P [...]

18
Sep
20200810 Hsiao C Epub
The study of isotopic enrichment of water in human plasma and erythrocyte

Dr. Hsiao C [...]

01
Sep
20200505 Wang AHJ paper photo Epub
Biochemical and molecular dynamics studies of archaeal polyisoprenyl pyrophosphate phosphatase from Saccharolobus solfataricus

Dr. Wang AH [...]

01
Sep
20200829 Wu SH paper photo
New Biscembranoids Sardigitolides A-D and Known Cembranoid-Related Compounds from Sarcophyton digitatum: Isolation, Structure Elucidation, and Bioactivities

Dr. Wu SH [...]

29
Aug
20200821 Bessho Y paper photo
Micro-liquid enclosure array and its semi-automated assembling system for x-ray free-electron laser diffractive imaging of samples in solution

Dr. Bessho Y [...]

21
Aug
20200820 Liao JC paper photo v2
Converting Escherichia coli to a Synthetic Methylotroph Growing Solely on Methanol

Dr. Liao JC [...]

20
Aug
20200714 Chen GC Epub photo
Aging shifts mitochondrial dynamics toward fission to promote germline stem cell loss

Dr. Yao CK & Dr. Chen GC [...]

18
Aug
20200724 Ho MC Epub photo
A carbohydrate-binding protein from the edible Lablab beans effectively blocks the infections of influenza viruses and SARS-CoV-2

Dr. Ho MC [...]

11
Aug
20200804 Wu KP paper photo
Insights Into Dynamics of Inhibitor and Ubiquitin-Like Protein Binding in SARS-CoV-2 Papain-Like Protease

Dr. Wu KP [...]

04
Aug
20200428 Lin HC paper photo 1
Discovery of a Dual Function Cytochrome P450 that Catalyzes Enyne Formation in Cyclohexanoid Terpenoid Biosynthesis

Dr. Lin HC & Dr. Lin CH [...]

03
Aug
20200409 Khoo KH paper photo
Mycobacterium bovis BCG infection alters the macrophage N-glycome

Dr. Khoo KH [...]

01
Aug
20200730 Chang MS paper photo
PHRF1 promotes migration and invasion by modulating ZEB1 expression

Dr. Chang MS [...]

30
Jul
20200625 Wang AHJ epub photo
Development of a Versatile and Modular Linker for Antibody-Drug Conjugates Based on Oligonucleotide Strand Pairing

Dr. Wang AH [...]

15
Jul
20200707 Lowary TL paper photo
Cryo-EM structure of arabinosyltransferase EmbB from Mycobacterium smegmatis

Dr. Lowary TL [...]

07
Jul
20200703 Khoo KH paper photo
Fucosyltransferase 4 shapes oncogenic glycoproteome to drive metastasis of lung adenocarcinoma

Dr. Khoo KH [...]

03
Jul
20200702 Chang MS paper photo
An important role of PHRF1 in dendritic architecture and memory formation by modulating TGF-β signaling

Dr. Chang MS [...]

02
Jul
20200701 Ko TP paper photo
Structural characterization of borneol dehydrogenase from Pseudomonas sp. TCU-HL1

Dr. Huang KF & Dr. Ko TP [...]

01
Jul
20200608 Wang YS research photo
Probing the Active Site of Deubiquitinase USP30 With Noncanonical Tryptophan Analogues

Dr. Wang YS & Dr. Tsai MD [...]

23
Jun
20200520 Khoo KH papaer photo
Strategic applications of negative mode LC-MS/MS analyses to expedite confident mass spectrometry-based identification of multiple glycosylated peptides

Dr. Khoo KH [...]

02
Jun
20200310 Khoo KH paper photo
Targeting glycosylated PD-1 induces potent anti-tumor immunity

Dr. Khoo KH [...]

01
Jun
2019 08 11 Liang PH New Epub
Targeting β-tubulin/CCT-β complex induces apoptosis and suppresses migration and invasion of highly metastatic lung adenocarcinoma

Dr. Liang PH [...]

31
May
20200526 Chi P research photo 1
Rad51 Facilitates Filament Assembly of Meiosis-Specific Dmc1 Recombinase

Dr. Chi P [...]

26
May
20200522 Yang WY paper photo
Vesicular Transport Mediates the Uptake of Cytoplasmic Proteins Into Mitochondria in Drosophila Melanogaster

Dr. Yang WY [...]

22
May
20200522 Lin S paper photo
Enhanced NK-92 Cytotoxicity by CRISPR Genome Engineering Using Cas9 Ribonucleoproteins

Dr. Lin S [...]

22
May
20200505 Lowary TL paper photo
Cryo-EM Structures and Regulation of Arabinofuranosyltransferase AftD from Mycobacteria

Dr. Lowary TL [...]

21
May
20200520 Khoo KH paper photo 2
Negative Ion Mode nanoLC-ESI-MS/MS Analyses of Permethylated Sulfated Glycans

Dr. Khoo KH [...]

20
May
20200520 Khoo KH paper photo 1
Permethylation and Microfractionation of Sulfated Glycans for MS Analysis

Dr. Khoo KH [...]

20
May
20200309 Lin CH paper photo 1
Substituent Position of Iminocyclitols Determines the Potency and Selectivity for Gut Microbial Xenobiotic-Reactivating Enzymes

Dr. Lin CH [...]

14
May
20200504 Chen RH paper photo
Tumor Suppressor Death-Associated Protein Kinase 1 Inhibits Necroptosis by p38 MAPK Activation

Dr. Chen RH [...]

04
May
20200325 Wu SH paper photo
Cyanine dye mediated mitochondrial targeting enhances the anti-cancer activity of small-molecule cargoes

Dr. Wu SH [...]

30
Apr
20200419 Angata T paper photo
Preparation of Recombinant Siglecs and Identification of Their Ligands

Dr. Angata T [...]

19
Apr
20200417 Lin HC paper photo
Enzyme-Catalyzed Azepinoindole Formation in Clavine Alkaloid Biosynthesis

Dr. Lin HC [...]

17
Apr
20200306 Wang YS paper photo
Linker and N-terminal domain engineering of pyrrolysyl-tRNA synthetase for substrate range shifting and activity enhancement

Dr. Wang YS [...]

07
Apr
20200403 Wu SH paper photo
H-Phosphonate Synthesis and Biological Evaluation of an Immunomodulatory Phosphoglycolipid from Thermophilic Bacteria

Dr. Wu SH [...]

03
Apr
20200401 Meng TC paper Photo
Targeting Protein Tyrosine Phosphatase PTP-PEST for Therapeutic Intervention in Acute Myocardial Infarction

Dr. Meng TC & Dr. Hsu SD [...]

01
Apr
20200313 Lin CH paper photo 1
Cholesteryl α-D-glucoside 6-acyltransferase enhances the adhesion of Helicobacter pylori to gastric epithelium

Dr. Lin CH [...]

13
Mar
2020310 Angata T paper photo
Siglecs that Associate with DAP12

Dr. Angata T [...]

10
Mar
20191219 Chen RH paper photo
Integrative analyses of noncoding RNAs reveal the potential mechanisms augmenting tumor malignancy in lung adenocarcinoma

Dr. Chen RH [...]

20
Feb
20200207 Bessho Y paper photo
Design of a liquid cell toward three-dimensional imaging of unidirectionally-aligned particles in solution using X-ray free-electron lasers

Dr. Bessho Y [...]

07
Feb
20200205 Hsu STD paper photo
A High-Throughput Interbacterial Competition Screen Identifies ClpAP in Enhancing Recipient Susceptibility to Type VI Secretion System-Mediated Attack by Agrobacterium tumefaciens

Dr. Hsu STD [...]

05
Feb
2020 02 04 Ho MC paper photo 1
Constructing a yeast to express the largest cellulosome complex on the cell surface

Dr. Ho MC [...]

04
Feb
2020 02 01 Hsu STD
Protein knots provide mechano-resilience to an AAA+ protease-mediated proteolysis with profound ATP energy expenses

Dr. Hsu SD [...]

01
Feb
20200128 Khoo KH paper photo
The nutrient sensor OGT regulates Hipk stability and tumorigenic-like activities in Drosophila

Dr. Khoo KH [...]

28
Jan
2020 UU4 IBC PR slide En
Cryo-EM analysis of a feline coronavirus spike protein reveals a unique structure and camouflaging glycans

Dr. Hsu STD & Dr. Khoo KH & Dr. Wu KP [...]

21
Jan
20200115 Chen RH paper photo
WD40 protein Wuho controls germline homeostasis via TRIM-NHL tumor suppressor Mei-p26 in Drosophila

Dr. Huang F & Dr. Chen RH [...]

15
Jan
20191126 TsaiMD paper photo
Disrupting the Conserved Salt Bridge in the Trimerization of Influenza A Nucleoprotein

Dr. Tsai MD [...]

09
Jan
20200107 Wang AHJ paper photo 0522
Structural basis of polyethylene glycol recognition by antibody

Dr. Wang AH [...]

07
Jan
20191205 Shih YL paper photo
Effector loading onto the VgrG carrier activates type VI secretion system assembly

Dr. Shih YL [...]

07
Jan
20200103 Angata T paper photo
Siglec-15: a potential regulator of osteoporosis, cancer, and infectious diseases

Dr. Angata T [...]

03
Jan
20200103 Chen RH paper photo
Cullin 3 and Its Role in Tumorigenesis

Dr. Chen RH [...]

03
Jan
20190925 Lin CH paper photo
Intracellular galectins control cellular responses commensurate with cell surface carbohydrate composition

Dr. Lin CH & Dr. Yang WY [...]

01
Jan
2019 12 26 Tsai MD 1
Temperature-Resolved Cryo-EM Uncovers Structural Bases of Temperature-Dependent Enzyme Functions

Dr. Tsai MD [...]

26
Dec
20191216 Chen RH paper photo
PSPC1-interchanged interactions with PTK6 and β-catenin synergize oncogenic subcellular translocations and tumor progression

Dr. Chen RH [...]

16
Dec
aculene biosynthesis Hsiao Ching Lin 1
The Biosynthesis of Norsesquiterpene Aculenes Requires Three Cytochrome P450 Enzymes to Catalyze a Stepwise Demethylation Process

Dr. Lin HC [...]

16
Dec
JCI125212.ga
HLA-B27-mediated activation of TNAP phosphatase promotes pathogenic syndesmophyte formation in ankylosing spondylitis

Dr. Angata T [...]

02
Dec
20191102 Wang AH
Chaetomella raphigera β-glucosidase D2-BGL has intriguing structural features and a high substrate affinity that renders it an efficient cellulase supplement for lignocellulosic biomass hydrolysis

Dr. Wang AH [...]

02
Nov
kaup a 1596484 f0001 oc
Suppression of autophagy during mitosis via CUL4-RING ubiquitin ligases-mediated WIPI2 polyubiquitination and proteasomal degradation

Dr. Chen RH [...]

02
Nov
2019 08 12 Chen GC Research Photo
PTPN3 suppresses lung cancer cell invasiveness by counteracting Src-mediated DAAM1 activation and actin polymerization

Dr. Chen GC [...]

31
Oct
F1.large
Sugar starvation-regulated MYBS2 and 14-3-3 protein interactions enhance plant growth, stress tolerance, and grain weight in rice

Dr. Lin SY [...]

22
Oct
20191021 ChenRH Research Photo
Ubiquitin-mediated regulation of autophagy

Dr. Chen RH [...]

21
Oct
Angata T 7/17 Research Photo
Expedient assembly of Oligo-LacNAcs by a sugar nucleotide regeneration system: Finding the role of tandem LacNAc and sialic acid position towards siglec binding

Dr. Angata T [...]

15
Oct
20191007 ANGATA T pub
Boronate affinity-based photoactivatable magnetic nanoparticles for the oriented and irreversible conjugation of Fc-fused lectins and antibodies

Dr. Angata T [...]

07
Oct
kaup a 1634444 f0001 c
Autophagy, Inflammation, and Metabolism (AIM) Center in its second year

Dr. Chen GC [...]

03
Oct
20190929 WU W J pub
Development of Novel Irreversible Pyruvate Kinase M2 Inhibitors

Dr. Wu WJ [...]

26
Sep
Chen RH -2019 ASB11 Research Photo
BIK ubiquitination by the E3 ligase Cul5-ASB11 determines cell fate during cellular stress

Dr. Chen RH & Dr. Lin SY [...]

02
Sep
20190831 CHEN SHUI TEIN pub
Medicinal Mushroom Taiwanofungus camphoratus: A potential cure for cancer

Dr. Chen ST [...]

31
Aug
20190827 Khoo
Functional roles of ST8SIA3-mediated sialylation of striatal dopamine D2 and adenosine A2A receptors

Dr. Khoo KH [...]

27
Aug
Lin et al 2019 Angewandte Chemie International Edition
Chemoenzymatic Synthesis of DSGb5 and Sialylated Globo-series Glycans

Dr. Angata T [...]

12
Aug
20190806 Chang CI- Resear Photo
Structural Basis for the Differential Regulatory Roles of the PDZ Domain in C-Terminal Processing Proteases

Dr. Chang CI & Dr. Ho MR [...]

06
Aug
1 s2 0 S0969212619301261 fx1 lrg
Untying a Knotted SPOUT RNA Methyltransferase by Circular Permutation Results in a Domain-Swapped Dimer

Dr. Hsu STD & Dr. Huang KF [...]

06
Aug
20190802 Lin CH Research Photo
Galectin-3 is required for the microglia-mediated brain inflammation in a model of Huntington’s disease

Dr. Lin CH [...]

02
Aug
18 2019 3145 Fig1 HTML
Protein arginine methyltransferases: insights into the enzyme structure and mechanism at the atomic level

Dr. Ho MC [...]

01
Aug
Liang PH 20190726 Research
Characterization of a Cis-Prenyltransferase from Lilium longiflorum Anther

Dr. Liang PH [...]

26
Jul
Yao 2019 07 18 Epub
A circuit-dependent ROS feedback loop mediates glutamate excitotoxicity to sculpt the Drosophila motor system

Dr. Yao CK [...]

18
Jul
20190711 Chen RH New Research Photo
LncRNA NORAD is repressed by the YAP pathway and suppresses lung and breast cancer metastasis by sequestering S100P

Dr. Chen RH [...]

11
Jul
2019 07 10 Meng TC's Publication
Nitrite Protects Neurons Against Hypoxic Damage Through S-nitrosylation of Caspase-6

Dr. Meng TC [...]

10
Jul
20190705 Wang AH Research Photo
Enhancement of laccase activity by pre-incubation with organic solvents

Dr. Wang AH [...]

05
Jul
20190704 Chen RH Research Photo
miR-103/107 prolong Wnt/β-catenin signaling and colorectal cancer stemness by targeting Axin2

Dr. Chen RH [...]

04
Jul
20190624 Chen RH Research Photo
Long non-coding RNA HOXB-AS3 promotes myeloid cell proliferation and its higher expression is an adverse prognostic marker in patients with acute myeloid leukemia and myelodysplastic syndrome

Dr. Chen RH [...]

24
Jun
42003 2019 458 Fig1 HTML
Thermococcus sp. 9°N DNA polymerase exhibits 3′-esterase activity that can be harnessed for DNA sequencing

Dr. Tsai MD & Dr. Wu WJ & Dr. Wang AH & Dr. Maestre-Reyna M [...]

20
Jun
20190605 Lin CH Research Photo
Bioorthogonal Fluorescent Nanodiamonds for Continuous Long-Term Imaging and Tracking of Membrane Proteins

Dr. Lin CH [...]

05
Jun
2019 1 2 Rita Chen1
Segments in the Amyloid Core that Distinguish Hamster from Mouse Prion Fibrils

Dr. Chen RP [...]

02
Jun
1 s2.0 S014181301836728X gr1
Crystal structure of the blue fluorescent protein with a Leu-Leu-Gly tri-peptide chromophore derived from the purple chromoprotein of Stichodactyla haddoni

Dr. Huang KF [...]

01
Jun
2019 06 11WJW 英
Human DNA Polymerase μ Can Use a Noncanonical Mechanism for Multiple Mn2+-mediated Functions

Dr. Tsai MD & Dr. Wu WJ & Dr. Maestre-Reyna M & Dr. Bessho Y [...]

29
May
F1.large
Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway

Dr. Chen RH & Dr. Lin SY [...]

17
May
20190516 Lee MT Research Photo
Blockage of glutamine-dependent anaplerosis affects mTORC1/2 activity and ultimately leads to cellular senescence-like response

Dr. Lee MT [...]

16
May
20190506 Lin CH Research Photo
Quantification and Imaging of Antigens on Cell Surface with Lipid-Encapsulated Fluorescent Nanodiamonds

Dr. Lin CH [...]

06
May
annrheumdis 2018 213799 F1.large
PTPN14 phosphatase and YAP promote TGFβ signalling in rheumatoid synoviocytes

Dr. Meng TC [...]

02
May
20190501 Lee MT Reaserch Photo
Reduction in MnSOD promotes the migration and invasion of squamous carcinoma cells

Dr. Lee MT [...]

01
May
2019 05 Wang AHJ
New paradigm of functional regulation by DNA mimic proteins: Recent updates

Dr. Wang AH [...]

01
May
2019 4 23 Shih1
Active Transport of Membrane Components by Self-Organization of the Min Proteins

Dr. Shih YL [...]

23
Apr
2019 04 17 Tsai MD
Use of Cryo-EM To Uncover Structural Bases of pH Effect and Cofactor Bispecificity of Ketol-Acid Reductoisomerase

Dr. Tsai MD [...]

17
Apr
1 s2 0 S1046202318303013 gr1
Deriving a sub-nanomolar affinity peptide from TAP to enable smFRET analysis of RNA polymerase II complexes

Dr. Lin SY [...]

15
Apr
253 2019 9708 Fig1 HTML
Detecting and prioritizing biosynthetic gene clusters for bioactive compounds in bacteria and fungi

Dr. Lin HC [...]

01
Apr
F3 large
TIM-mediated inhibition of HIV-1 release is antagonized by Nef but potentiated by SERINC proteins

Dr. Lin S [...]

19
Mar
1 s2.0 S0959440X1830068X fx1 lrg
Advances toward mapping the full extent of protein site-specific O-GalNAc glycosylation that better reflects underlying glycomic complexity

Dr. Khoo KH [...]

15
Mar
2019 3 14 Wang AH
An Effective Neutralizing Antibody Against Influenza Virus H1N1 from Human B Cells

Dr. Wang AH [...]

14
Mar
41467 2019 8924 Fig1 HTML
Omegasome-proximal PtdIns(4,5)P2 couples F-actin mediated mitoaggregate disassembly with autophagosome formation during mitophagy

Dr. Yang WY [...]

27
Feb
2019 2 19 Ho MC
Regulatory cascade involving transcriptional and N-end rule pathways in rice under submergence

Dr. Ho MC & Dr. Wu WJ [...]

19
Feb
20190103 1
One-Pot Bioconversion of L-Arabinose to L-Ribulose in an Enzymatic Cascade

Dr. Lin CH [...]

18
Feb
2019 2 15 Hsu STD
Untying a Protein Knot by Circular Permutation

Dr. Hsu SD [...]

15
Feb
2019 2 1 Liang PH
Engineer multi-functional cellulase/xylanase/β-glucosidase with improved efficacy to degrade rice straw

Dr. Liang PH [...]

01
Feb
cwy095f01
Helicobacter pylori induces intracellular galectin-8 aggregation around damaged lysosomes within gastric epithelial cells in a host O-glycan-dependent manner

Dr. Lin CH [...]

01
Feb
20190201 1
Catalytic mechanism of DNA polymerases-Two metal ions or three?

Dr. Tsai MD [...]

01
Feb
ijms 20 00622 ag
Novel Zebrafish Mono-α2,8-sialyltransferase (ST8Sia VIII): An Evolutionary Perspective of α2,8-Sialylation

Dr. Khoo KH [...]

31
Jan
c8ob02774a
Biosynthesis of bioactive natural products from Basidiomycota

Dr. Lin HC [...]

31
Jan
1 s2 0 S2589004218302517 fx1
Srv2 Is a Pro-fission Factor that Modulates Yeast Mitochondrial Morphology and Respiration by Regulating Actin Assembly

Dr. Yang WY [...]

25
Jan
20190118 3
Diverse Synthesis of Natural Trehalosamines and Synthetic 1,1′-Disaccharide Aminoglycosides

Dr. Lin CH [...]

18
Jan
20190118 2
Binding and Enhanced Binding between Key Immunity Proteins TRAF6 and TIFA

Dr. Tsai MD & Dr. Maestre-Reyna M & Dr. Bessho Y [...]

18
Jan
20190118 1
Crystal Structures of the C-Terminally Truncated Endoglucanase Cel9Q from Clostridium thermocellum Complexed with Cellodextrins and Tris

Dr. Wang AH [...]

18
Jan
2019 1 18 Wang AH
Crystal Structure of PigA: A Prolyl Thioester-Oxidizing Enzyme in Prodigiosin Biosynthesis

Dr. Wang AH [...]

18
Jan
wu201901
Synthesis of the trisaccharide repeating unit of capsular polysaccharide from Klebsiella pneumoniae

Dr. Wu SH [...]

17
Jan
2019 1 18 Peter Chi
Promotion of homology-directed DNA repair by polyamines

Dr. Chi P [...]

08
Jan
mic 06 065 g003
Guidelines for DNA recombination and repair studies: Mechanistic assays of DNA repair processes

Dr. Chi P [...]

07
Jan
432348 1 En 40 Fig1 HTML
Triggering Mitophagy with Photosensitizers

Dr. Yang WY [...]

05
Jan
kmab a 1541370 f0001 c
Antibody-drug conjugates with HER2-targeting antibodies from synthetic antibody libraries are highly potent against HER2-positive human gastric tumor in xenograft models

Dr. Wang AH [...]

03
Jan
2019 1 1 Chen H
SFRP3 negatively regulates placental extravillous trophoblast cell migration mediated by the GCM1-WNT10B-FZD7 axis

Dr. Chen Hungwen [...]

01
Jan
2018 12 21 Angata
Soluble Siglec-14 glycan-recognition protein is generated by alternative splicing and suppresses myeloid inflammatory responses

Dr. Angata T & Dr. Hsu SD [...]

21
Dec
2018 12 14 Wang AH
The C-terminal D/E-rich domain of MBD3 is a putative Z-DNA mimic that competes for Zα DNA-binding activity

Dr. Wang AH & Dr. Ho MR [...]

14
Dec