Tumor suppressor p16
[Mol. Cell 1, 421 (1998)]
DNA polymerase X from ASFV
[Nature Struc. Biol. (2001)]

Enzymology of
Phospholipase A2
[Chemical Reviews (2001)]

[Nature Struc. Mol. Biol.  (2005)]

Mechanism of DNA polymerases
[Chemical Reviews  (2006)]

The ARID domain of RBP2
[Nature Struc. Mol. Biol. (2008)]

Dun1 FHA -
diphosphorylated SCD
[Molecular Cell (2008)]

FHA domain review
[Science Signaling (2008)]


NP as a new anti-influenza target
[PNAS (2011)]

FHA-pT binding of TIFA activates NF-κB
[MCB (2012)]

Rad53 activation by
quantitative MS
[MCP (2014)]

Non-Watson-Crick pairing by Pol X
[JACS (2014)]


Fidelity modulation of Pol λ
[JACS (2016)]

TIFA and inflammasome
[PNAS (2016)]

TIFA and leukemia
[Cancer Research (2017)]

How DNA polymerases catalyze
replication and repair with
contrasting fidelity (2017)


Cryo-EM in enzymology
[JACS (2019)]

Mn2+ specificity of Pol μ
[JACS (2019)]

3’-esterase for DNA seq
[Commun. Biol. (2019)]

Temp-resolved Cryo-EM
[JACS (2019)]


Current Research Projects:
Taiwan Protein Project (TPP)
FHA Signaling and Phosphoproteomics
Tumor Suppressors and Cancer Proteins
Histone Demethylases and RBP2
Kinetic Mechanism and Structures of DNA Polymerases
Drug Discovery against Influenza Virus
Past Research Projects (Mechanistic Enzymology):
Capsular Polysaccharide Biosynthesis of K. pneumoniae (2005-2012)
Phosphatidyl Inositide-specific Phospholipase C (1992-2005)
Phospholipase A2 (PLA2) (1988-2004)
Adenylate Kinase (1985-96)
Phospholipids Chiral at Phosphorus (1982-92)
Quadrupolar NMR in Biology (1982-89)
Chiral Phosphates (1979-84)


C. V. and Publication List
中 文 簡 歷