aculene biosynthesis Hsiao Ching Lin 1

The Biosynthesis of Norsesquiterpene Aculenes Requires Three Cytochrome P450 Enzymes to Catalyze a Stepwise Demethylation Process

Angew Chem Int Ed Engl. 2019 Dec 16;58(51):18414-18418
doi: 10.1002/anie.201910200

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Graphical Abstract

The Biosynthesis of Norsesquiterpene Aculenes Requires Three Cytochrome P450 Enzymes to Catalyze a Stepwise Demethylation Process