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Dr. Po-Chen Chu
Assistant Research Specialist
Room 801, Institute of Biological Chemistry, Academia Sinica
128, Academia Road Sec. 2, Nankang, Taipei 115, Taiwan
TEL: +886-2-02-27855696 ext. 8011
FAX: +886-2-02-27889759
chupc@gate.sinica.edu.tw

Targeting the Warburg effect of cancer cells by novel energy restriction-mimetic agents.

Identification and targeting the novel KRAS regulatory loop in pancreatic cancer cells.

2005,09 - 2010,02 Ph.D., Institute of Biochemical Sciences, National Taiwan University
1999,09 - 2001,06 M.S., Institute of Molecular Medicine, National Cheng Kung University
1995,09 - 1999,06 B.S., Department of Medical Laboratory Science and Biotechnology, National Cheng Kung University

2015,02 - present Assistant Research Specialist, Institute of Biological Chemistry, Academia Sinica
2014,02 - 2015,01 Research Assistant Professor, Institute of Basic Medical Sciences, National Cheng Kung University
2013,07 - 2014,01 Postdoctoral Fellow, Graduate Institute of Clinical Medicine, National Cheng Kung University
2010,03 - 2013,06 Postdoctoral Fellow, College of Pharmacy, The Ohio State University

SP's Publications

    Publication List
Insulin-like growth factor-I receptor is suppressed through transcriptional repression and mRNA destabilization by a novel energy restriction-mimetic agent.
Chu PC, Kulp SK, Chen CS. Carcinogenesis (2013)
Suppression of prostate epithelial proliferation and intraprostatic progrowth signaling in transgenic mice by a new energy restriction-mimetic agent.
Berman-Booty LD, Chu PC, Thomas-Ahner JM, Bolon B, Wang D, Yang T, Clinton SK, Kulp SK, Chen CS. Cancer Prevention Research (2013)
The mRNA-stabilizing factor HuR protein is targeted by β-TrCP protein for degradation in response to glycolysis inhibition.
Chu PC, Chuang HC, Kulp SK, Chen CS. Journal of Biological Chemistry (2012)
Targeting the oncogenic E3 ligase Skp2 in prostate and breast cancer cells with a novel energy restriction-mimetic agent.
Wei S, Chu PC, Chuang HC, Hung WC, Kulp SK, Chen CS. PLoS One (2012)
Development of a novel class of glucose transporter inhibitors.
Wang D*, Chu PC*, Yang CN, Yan R, Chuang YC, Kulp SK, Chen CS. Journal of Medicinal Chemistry (2012)
Disruption of murine mp29/Syf2/Ntc31 gene results in embryonic lethality with aberrant checkpoint response.
Chen CH*, Chu PC*, Lee L, Lien HW, Lin TL, Fan CC, Chi P, Huang CJ, Chang MS. PLoS One (2012)
Energy restriction-mimetic agents induce apoptosis in prostate cancer cells in part through epigenetic activation of KLF6 tumor suppressor gene expression.
Chen CH, Huang PH, Chu PC, Chen MC, Chou CC, Wang D, Kulp SK, Teng CM, Wang Q, Chen CS. Journal of Biological Chemistry (2011)
hPuf-A/KIAA0020 modulates PARP-1 cleavage upon genotoxic stress.
Chang HY, Fan CC, Chu PC, Hong BE, Lee HJ, Chang MS. Cancer Research (2011)

Updated 2013.09.12

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