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Dr. Yun Yen
Joint Appointment Research Fellow
TEL: +886-2-27361661 ext. 2008
FAX: +886-2-23787795

Clinical Oncology, cancer drug development, translational medicine

1985,09 - 1988,12 Ph.D., Pathology and Cell Biology, Thomas Jefferson University
1975,09 - 1982,06 MD, School of Medicine, Taipei Medical College

2014 - present Joint Appointment Research Fellow, Institute of Biological Chemistry, Academia Sinica
2011,08 - present The Ph.D. program for Cancer Biology and Drug Discovery ,Professor, Taipei Medical University
2011,08 - 2017,07 President, Taipei Medical University
2003,04 - 2011,07 City of Hope, National Medical Center, Professor

    Publications List
1,4-Naphthoquinones as inhibitors of Itch, a HECT domain-E3 ligase, and tumor growth suppressors in multiple myeloma.
Liu YM, HuangFu WC, Huang HL, Wu WC, Chen YL, Yen Y, Huang HL, Nien CY, Lai MJ, Pan SL, Liou JP. Eur J Med Chem. (2017)
Benzodiazepines use and breast cancer risk: A population-based study and gene expression profiling evidence.
Iqbal U, Chang TH, Nguyen PA, Syed-Abdul S, Yang HC, Huang CW, Atique S, Yang WC, Moldovan M, Jian WS, Hsu MH, Yen Y, Jack Li YC. J Biomed Inform. (2017)
Global DNA methylation analysis reveals miR-214-3p contributes to cisplatin resistance in pediatric intracranial nongerminomatous malignant germ cell tumors.
Hsieh TH, Liu YR, Chang TY, Liang ML, Chen HH, Wang HW, Yen Y, Wong TT. Neuro Oncol. (2017)
Human mitochondrial pyrroline-5-carboxylate reductase 1 promotes invasiveness and impacts survival in breast cancers.
Ding J, Kuo ML, Su L, Xue L, Luh F, Zhang H, Wang J, Lin TG, Zhang K, Chu P, Zheng S, Liu X, Yen Y. Carcinogenesis. (2017)
Long noncoding RNA LncHIFCAR/MIR31HG is a HIF-1a co-activator driving oral cancer progression.
Jing-Wen Shih, Wei-Fan Chiang, Alexander T.H. Wu, Ming-Heng Wu, Ling-Yu Wang, Yen-Ling Yu, Yu-Wen Hung, Wen-Chang Wang, Cheng-Ying Chu, Chiu-Lien Hung, Chun A. Changou, Yen Y & Hsing-Jien Kung. Nature Communications. (2017)
Mechanism and Clinical Properties of StemBios Cell Therapy: Induction of Early Osseointegration in Novel Dental Implants.
Weng CC, Ou KL, Wu CY, Huang YH, Wang J, Yen Y, Cheng HY, Lin YH. Int J Oral Maxillofac Implants. (2017)
Ovatodiolide suppresses colon tumorigenesis and prevents polarization of M2 tumor-associated macrophages through YAP oncogenic pathways.
Huang YJ, Yang CK, Wei PL, Huynh TT, Whang-Peng J, Meng TC, Hsiao M, Tzeng YM, Wu AT, Yen Y. J Hematol Oncol. (2017)
Overexpression of Uridine-Cytidine Kinase 2 Correlates with Breast Cancer Progression and Poor Prognosis.
Guosong Shen, Pingya He, Yingying Mao, Peipei Li, Frank Luh, Guohui Ding, Xiyong Liu, Yun Yen. Breast Cancer (2017)
Phase IB trial of ixabepilone and vorinostat in metastatic breast cancer.
Luu T, Kim KP, Blanchard S, Anyang B, Hurria A, Yang L, Beumer JH, Somlo G, Yen Y. Breast Cancer Res Treat. (2017)
Tyrosine kinase inhibitors for advanced or metastatic thyroid cancer: a meta-analysis of randomized controlled trials.
Liu JW, Chen C, Loh EW, Chu CC, Wang MY, Ouyang HJ, Chang YT, Zhuang WZ, Chou CW, Huang DJ, Lee CH, Yen Y, Tam KW. Curr Med Res Opin. (2017)

Updated 2018.08.01

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